Khan Nisar, Jadoon Huma, Zaman Munawar, Ahmed Ashfaq
Department of Pathology, Kohat Institute of Medical Sciences, Kohat, Pakistan.
J Ayub Med Coll Abbottabad. 2009 Jan-Mar;21(1):116-8.
Pleural effusion is the abnormal collection of fluid in the pleural space resulting from excessive fluid production or decreased absorption and it is one of the most common clinical conditions that we come across in pulmonology clinics and in hospitals. The objective of prospective study was to evaluate the diagnostic role of Abrams Needle Biopsy in Exudative Pleural Effusion.
The study was performed at the Department of Pulmonology, Ayub Teaching Hospital, Abbottabad over a period of 1 year, i.e., January 2008 to December 2008. Sixty-three patients of either sex and all ages with exudative pleural effusion, on whom Abrams Needle Biopsy was performed were included in the study. Minimum of four specimens from each patient were taken and histopathology done.
Out of 63 patients, histopathology revealed the cause in 60 (95%) cases. Tuberculosis, malignancy and rheumatoid pleurisy were confirmed in 34, 24, and 2 cases respectively. Specimens of3 patients did not reveal any result and showed non-specific inflammation and were further investigated accordingly.
The diagnostic yield of Biopsy was 95%. Pleural biopsy is still a reliable and valuable investigation in diagnosing pleural effusion, provided that adequate pleural specimen is taken.
胸腔积液是指胸腔内液体异常积聚，其原因是液体产生过多或吸收减少，它是我们在肺科诊所和医院中最常见的临床病症之一。前瞻性研究的目的是评估亚伯拉姆斯针吸活检在渗出性胸腔积液中的诊断作用。
该研究在阿伯塔巴德阿尤布教学医院肺科进行，为期1年，即2008年1月至2008年12月。纳入研究的63例患者均为渗出性胸腔积液患者，不限性别和年龄，均接受了亚伯拉姆斯针吸活检。每位患者至少采集4份标本并进行组织病理学检查。
63例患者中，组织病理学检查在60例（95%）患者中明确了病因。分别确诊为结核病、恶性肿瘤和类风湿性胸膜炎的患者有34例、24例和2例。3例患者的标本未得出任何结果，显示为非特异性炎症，并据此进一步进行了检查。
活检的诊断阳性率为95%。只要获取足够的胸腔标本，胸膜活检在诊断胸腔积液方面仍然是一项可靠且有价值的检查。
