Cytogenetic study of a nodular hyperplasia of the thyroid after irradiation for Hodgkin's disease.
作者信息
van den Berg E, van Doormaal J J, Oosterhuis J W, de Jong B, Buist J, Vos A M, Dam A, Vermeij A
机构信息
Department of Pathology, University of Groningen, The Netherlands.
出版信息
Cancer Genet Cytogenet. 1991 May;53(1):15-21. doi: 10.1016/0165-4608(91)90110-g.
PMID:2036636
Abstract
We describe cytogenetics of a case of nodular hyperplasia of the thyroid with papillary microcarcinoma following radiotherapy for Hodgkin's disease. The chromosomal pattern found was very heterogeneous with a clonal abnormality of chromosome 10, among others. Together with some recent data from the literature, this finding may point to an important role of chromosome 10 abnormalities in the pathogenesis of benign and malignant thyroid neoplasms.
摘要
Zotero 插件