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粪肠球菌肺脓肿:一例报告及文献复习

[Enterococcus faecium lung abscess: one case report and literature review].

作者信息

Fang Xiang-Qun, Liu You-Ning

机构信息

Department of Respiratory Medicine, Chinese PLA General Hospital, Beijing 100853, China.

出版信息

Zhonghua Jie He He Hu Xi Za Zhi. 2010 Feb;33(2):99-103.

PMID:20367948
Abstract

OBJECTIVE

to study the diagnosis and treatment of enterococcus faecium lung abscess.

METHODS

a retrospective analysis of one case of Enterococcus faecium lung abscess and literature review was conducted.

RESULTS

this patient suffered from cough and sputum over 6 months and complicated with hemoptysis over 3 months. Pulmonary embolism and lung cancer were suspected initially. After 2 times of CT-guided percutaneous transthoracic needle aspiration biopsy the diagnosis of pneumonia was made in other hospitals. However, the consolidation in the lung progressed and cavity appeared although antibiotic therapy was conducted. After admission to our hospital, CT-guided percutaneous transthoracic needle aspiration biopsy was made and the lung tissue was sent for bacterial culture. Enterococcus faecium was cultured and it was susceptible to vancomycin, teicoplanin and linezolid. The disease improved significantly after treatment with these 3 antibiotics in turn. In addition, 13 cases of enterococcus pneumonia or lung abscess were reviewed, including 3 cases of enterococcus faecium lung abscess.

CONCLUSIONS

enterococcus faecium is rarely a pathogen for lung abscess. The diagnosis of enterococcus faecium lung abscess could be confirmed by lung biopsy and bacterial culture of lung tissue which could also provide the susceptibility of antibiotics and guide the antibiotic therapy.

摘要

目的

探讨粪肠球菌肺脓肿的诊断与治疗。

方法

对1例粪肠球菌肺脓肿患者进行回顾性分析并复习相关文献。

结果

该患者咳嗽、咳痰6个月余,伴咯血3个月余。最初怀疑为肺栓塞和肺癌。在外院经2次CT引导下经皮肺穿刺针吸活检后诊断为肺炎。然而,尽管进行了抗生素治疗,肺部实变仍进展并出现空洞。入院后,再次行CT引导下经皮肺穿刺针吸活检,并将肺组织送检进行细菌培养。培养出粪肠球菌,对万古霉素、替考拉宁和利奈唑胺敏感。依次使用这3种抗生素治疗后病情明显改善。此外,复习了13例肠球菌肺炎或肺脓肿病例,其中包括3例粪肠球菌肺脓肿。

结论

粪肠球菌很少作为肺脓肿的病原菌。粪肠球菌肺脓肿的诊断可通过肺活检及肺组织细菌培养来确诊,其还能提供抗生素敏感性并指导抗生素治疗。

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