Whitelaw W A
Division of Respiratory Medicine and Critical Care, Faculty of Medicine, University of Calgary, Alberta, Canada.
Chest. 1991 Jun;99(6):1507-10. doi: 10.1378/chest.99.6.1507.
Deaths from asthma seem to be increasing in spite of considerable improvements in drug treatment and management plans. There are many hypotheses to explain this, but little emphasis has been placed on the possibility that confidence in better drug treatments may modify patients' behavior so as to place them at greater risk of illness. It is well recognized that excessive confidence in bronchodilator inhalers and nebulizers can make patients stay away from hospitals too long during acute attacks. It is also very possible that prevention of symptoms by use of antiasthma drugs could allow patients to spend more time in environments containing antigens or other agents that provoke asthma, resulting in more serious and long-lasting bronchial inflammation and reactivity.
尽管药物治疗和管理方案有了显著改进，但哮喘导致的死亡人数似乎仍在增加。对此有许多假说，但很少有人强调这样一种可能性，即对更好药物治疗的信心可能会改变患者的行为，从而使他们面临更大的患病风险。众所周知，对支气管扩张剂吸入器和雾化器过度自信会使患者在急性发作时太长时间不去医院。使用抗哮喘药物预防症状也很可能会让患者在含有引发哮喘的抗原或其他物质的环境中停留更长时间，从而导致更严重、更持久的支气管炎症和反应性。
