Xu Jian-Chun, Lu Qi-Ming, Fu Li-Jie, Chen Yu-Ping
Department of Andrology, The First Affiliated Hospital of Kunming Medical College, Kunming, Yunnan 650032, China.
Zhonghua Nan Ke Xue. 2010 Feb;16(2):183-6.
Few double-blind controlled trials have been reported on Chinese patent medicines for the treatment of chronic prostatitis. The purpose of this study was to investigate the therapeutic efficacy of Qianlie Jiedu Capsule for chronic prostatitis (CP) by the randomized double-blind controlled method.
Eighty CP patients were equally randomized into an experimental and a control group, the former treated with Qianlie Jiedu Capsule + Rufloxacin, and the latter given placebo + Rufloxacin, both for 4 weeks. All the patients were evaluated by NIH-CPSI and EPS examination before and after the medication.
After 4-week treatment, the total score of NIH-CPSI and the scores of pain, voiding symptoms and quality of life were significantly decreased in both groups compared with the baseline (P < 0.05), so did the leukocyte count in EPS (P < 0.05). And the experimental group showed significant drops in the above scores as compared with the control (P < 0.05), except in the leukocyte count in EPS (P > 0.05).
Qianlie Jiedu Capsule combined with Rufloxacin is highly effective for CP by relieving pain and voiding symptoms,decreasing the leukocyte count in EPS and improving the life quality of the patients.
关于治疗慢性前列腺炎的中成药的双盲对照试验报道较少。本研究旨在采用随机双盲对照方法探讨前列解毒胶囊治疗慢性前列腺炎（CP）的疗效。
80例CP患者被等分为试验组和对照组，前者接受前列解毒胶囊+芦氟沙星治疗，后者给予安慰剂+芦氟沙星治疗，疗程均为4周。所有患者在用药前后均通过NIH-CPSI和EPS检查进行评估。
治疗4周后，与基线相比，两组的NIH-CPSI总分以及疼痛、排尿症状和生活质量评分均显著降低（P<0.05），EPS中的白细胞计数也显著降低（P<0.05）。与对照组相比，试验组上述评分显著下降（P<0.05），但EPS中的白细胞计数除外（P>0.05）。
前列解毒胶囊联合芦氟沙星对CP疗效显著，可缓解疼痛和排尿症状，降低EPS中的白细胞计数，并提高患者的生活质量。
