UNLABELLED

Coxarthrosis used to be referred to as the "doctors' cross" pointing to the difficulties of the treatment. Degenerative processes in the bones usually concern large joints: knee joints in 25-40% of cases, similarly in case of hip joints. Because of the role the joints play, the arthrosis may result in physical limitations or disability. The aim of the study was to evaluate the activity of catalase and superoxide dismutase (CuZn-SOD) in erythrocytes in patients suffering from the coxarthrosis--as the studied group and in healthy people--as the control group.

MATERIALS AND METHODS

Determining the activity of catalase and superoxide dismutase in the group of 17 patients hospitalized because of coxarthrosis.

RESULTS

In the study about 90% increase of the activity of the enzymes was determined in the studied group, in which the chemical compound 3{(2-aminothiazolyl)methylene}4H-1-benzopyran-4-one was added to the blood, in comparison with the control group.

CONCLUSION

The results of the test on catalase and superoxide dismutase clearly indicate that the free radicals participate in the whole course of coxarthrosis.