围产期李斯特菌病：加拿大2008年疫情
Perinatal listeriosis: Canada's 2008 outbreaks.
作者信息
Taillefer Catherine, Boucher Marc, Laferrière Céline, Morin Lucie
机构信息
Department of Obstetrics and Gynecology, CHU Ste-Justine, Université de Montréal, Montreal QC.
Department of Microbiology and Immunology, CHU Ste-Justine, Université de Montréal, Montreal QC.
出版信息
J Obstet Gynaecol Can. 2010 Jan;32(1):45-48. doi: 10.1016/S1701-2163(16)34403-6.
BACKGROUND
Listeriosis is one of the most severe foodborne illnesses worldwide. Most infections with Listeria are sporadic, but outbreaks do occur. Pregnant women exposed to this organism are at increased risk of chorioamnionitis, preterm labour, prematurity and intrauterine fetal demise. Severe neonatal infection can also occur.
CASES
Two recent outbreaks in Canada prompted a reassessment of the prevalence and the perinatal impact of this disease. We describe here three cases of perinatal listeriosis. The aim of our report is to demonstrate the variable clinical presentations and to emphasize the difficulty in diagnosing perinatal listeriosis.
CONCLUSION
Perinatal listeriosis is a severe disease with many possible clinical presentations. Clinical diagnosis may be difficult, so clinicians must maintain a high index of suspicion.
背景
李斯特菌病是全球最严重的食源性疾病之一。大多数李斯特菌感染为散发性，但也会暴发疫情。接触该病原体的孕妇发生绒毛膜羊膜炎、早产、胎膜早破和宫内胎儿死亡的风险增加。也可发生严重的新生儿感染。
病例
加拿大最近的两次疫情促使人们重新评估该病的患病率及其对围产期的影响。我们在此描述三例围产期李斯特菌病病例。我们报告的目的是展示其多样的临床表现，并强调围产期李斯特菌病诊断的困难。
结论
围产期李斯特菌病是一种严重疾病，有多种可能的临床表现。临床诊断可能困难，因此临床医生必须保持高度的怀疑指数。
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