Smíšková Dita, Karpíšková Renata, Džupová Olga, Marešová Vilma
1st Department of Infectious Diseases, Charles University Prague, Prague, Czech Republic.
Klin Mikrobiol Infekc Lek. 2010 Dec;16(6):211-4.
Listeria monocytogenes is ubiquitous in nature, being commonly present in faecal flora of otherwise healthy human population or animals. Clinical manifestation of listeria infection may vary widely from mild to invasive, life-threatening disease. In an immunocompromised host, a rather serious course should be expected. Due to cell-mediated immune insufficiency associated with pregnancy even a short bacteraemia in pregnant women can result in transplacental infection. Most listeria infections are sporadic but outbreaks may occur. An outbreak of listeriosis in the Czech Republic in the autumn of 2006 and winter of 2007 was associated with an increased incidence of perinatal listeriosis. More information on listeriosis prevention in pregnancy should be given and each febrile episode during pregnancy should be carefully examined. Early treatment of listeriosis reduces the risk of vertical transmission.
单核细胞增生李斯特菌在自然界中无处不在,常见于健康人群或动物的粪便菌群中。李斯特菌感染的临床表现差异很大,从轻度到侵袭性、危及生命的疾病都有可能。在免疫功能低下的宿主中,病情往往较为严重。由于妊娠相关的细胞介导免疫功能不足,孕妇即使出现短暂菌血症也可能导致经胎盘感染。大多数李斯特菌感染是散发性的,但也可能发生暴发。2006年秋季和2007年冬季捷克共和国发生的一次李斯特菌病暴发与围产期李斯特菌病发病率增加有关。应提供更多关于孕期预防李斯特菌病的信息,孕期每一次发热发作都应仔细检查。早期治疗李斯特菌病可降低垂直传播的风险。