Department of Rheumatology, The Hospital for Rheumatic Diseases, Hanyang University College of Medicine, Seoul, Korea.
Int J Rheum Dis. 2009 Jul;12(2):166-9. doi: 10.1111/j.1756-185X.2009.01400.x.
The association of malignancy with dermatomyositis is well known, and the frequency is reported to be up to 30%. However, cutaneous lymphoma associated with dermatomyositis has rarely been reported. We experienced a case of nasal-type NK/T-cell lymphoma in a 40-year-old woman with a 2-year history of dermatomyositis. To our knowledge, this is the first report of cutaneous involvement of nasal-type NK/T-cell lymphoma developing in a dermatomyositis patient. When skin lesions are resistant to aggressive conventional treatment in dermatomyositis patients, we should consider the possibility of malignancy, especially cutaneous lymphoma.
皮肤恶性肿瘤与皮肌炎相关，其发病率高达 30%。然而，皮肌炎合并皮肤淋巴瘤的病例却很少见。我们遇到一例 40 岁女性，患皮肌炎 2 年，出现鼻腔 NK/T 细胞淋巴瘤。据我们所知，这是首例皮肌炎患者发生鼻腔 NK/T 细胞淋巴瘤皮肤受累的病例。当皮肌炎患者的皮肤病变对积极的常规治疗无反应时，我们应考虑恶性肿瘤的可能性，尤其是皮肤淋巴瘤。
