Department of Health Behavior, Roswell Park Cancer Institute, Buffalo, NY, USA.
BMC Public Health. 2010 Apr 7;10:181. doi: 10.1186/1471-2458-10-181.
The offer of free nicotine replacement therapy (NRT) can be a cost-effective marketing strategy to induce smokers to call a telephone quitline for quitting assistance. However, the most cost-effective supply of free NRT to provide to smokers who call a quitline remains unknown. This study tests the hypothesis that smokers who call a telephone quitline and are given more free nicotine patches would report higher quit rates upon follow-up 12 months later.
A quasi-experimental design was used to assess nicotine patch usage patterns and quit rates among five groups of smokers who called the New York State Smokers' Quitline (NYSSQL) between April 2003 and May 2006 and were mailed 2-, 4-, 6- or 8-week supplies of free nicotine patches. The study population included 2,442 adult (aged 18 years or older) current daily smokers of 10 or more cigarettes per day, who were willing to make a quit attempt, and reported no contraindications for using the nicotine patch. Outcome variables assessed included the percentage of smokers who reported that they had not smoked for at least 7-days at the time of a 12 months telephone follow-up survey, sustained quitting, delayed quitting and nicotine patch use.
Quit rates measured at 12 months were higher for smokers in the groups who received either 2, 6, or 8 weeks of free patches. The lowest quit rate was observed among the group of Medicaid/uninsured smokers who were eligible to receive up to six weeks of free patches. The quit rate for the 4-week supply group did not differ significantly from the 6-week or 8-week groups. These patterns remained similar in an intent-to-treat analysis of 12-month quit rates and in an analysis of sustained quitting.
No clear cut dose response relationship was observed between the number of free nicotine patches sent to smokers and smoking outcomes. Baseline differences in the characteristics of the groups compared could account for the null findings, and a more definitive randomized trial is warranted.
提供免费尼古丁替代疗法(NRT)可能是一种具有成本效益的营销策略,可以促使吸烟者致电戒烟热线寻求戒烟帮助。然而,为致电戒烟热线的吸烟者提供免费 NRT 的最具成本效益的供应方式仍不清楚。本研究检验了以下假设:向致电戒烟热线的吸烟者提供更多免费尼古丁贴片会导致他们在 12 个月的随访时报告更高的戒烟率。
使用准实验设计评估了 2003 年 4 月至 2006 年 5 月期间致电纽约州吸烟者戒烟热线(NYSSQL)的五组吸烟者的尼古丁贴片使用模式和戒烟率,并向他们邮寄了 2 周、4 周、6 周或 8 周的免费尼古丁贴片供应。研究人群包括 2442 名成年(年龄在 18 岁或以上)、每天吸烟 10 支或更多支的当前每日吸烟者,他们愿意尝试戒烟,并且没有使用尼古丁贴片的禁忌症。评估的结果变量包括报告在 12 个月电话随访调查时至少 7 天未吸烟的吸烟者比例、持续戒烟、延迟戒烟和尼古丁贴片使用。
在接受 2、6 或 8 周免费贴片的组中,12 个月时的戒烟率更高。在有资格获得最多 6 周免费贴片的医疗补助/无保险吸烟者中,观察到的戒烟率最低。4 周供应组的戒烟率与 6 周或 8 周组无显著差异。在 12 个月戒烟率的意向治疗分析和持续戒烟分析中,这些模式仍然相似。
向吸烟者发送的免费尼古丁贴片数量与吸烟结果之间没有明显的剂量反应关系。与组间比较的基线特征差异可能导致了无效结果,需要进行更明确的随机试验。