Department of Internal Medicine, Louisiana State University Health Sciences Center - Shreveport, USA.
Am J Med Sci. 2010 Jun;339(6):516-8. doi: 10.1097/MAJ.0b013e3181d94f7a.
Treatment outcomes of end-stage renal disease (ESRD) vary significantly between European, Japanese, and American populations. The Dialysis Outcomes and Practice Patterns Study (DOPPS) described multiple differences between these cohorts; however, remarkable outcome differences exist among regions within the American population. Southern networks continue to have higher degrees of adverse outcomes despite improvements in healthcare delivery.
We examined the demographic indices and the degree of nonadherence to dialysis prescription among a sample of 97 patients with ESRD from the Northwestern Louisiana, Southern Arkansas and Northeast Texas area through face-to-face interviews and chart review and compared them with the published DOPPS results.
We found a significant difference between this Southern ESRD population and the overall American DOPPS cohort in demographics and dialysis adherence. Most (95.8%) patients were of African American ancestry and had a longer vintage on dialysis. Most patients were nonadherent as assessed by 2 of 4 measures of dialysis adherence: 29.2% of patients did not attend at least 1 dialysis session per month, and 86.4% shortened their dialysis session by 10 minutes or more at least 1 per month. These parameters were identified as major risk factors for adverse outcome in the DOPPS study.
This Southern patient cohort is different from the rest of the American ESRD population in terms of important measures of dialysis adherence. Such differences might contribute to our understanding of regional disparity in outcomes.
终末期肾病(ESRD)的治疗结果在欧洲、日本和美国人群之间存在显著差异。透析结果和实践模式研究(DOPPS)描述了这些队列之间的多个差异;然而,在美国人群中,不同地区之间存在显著的结果差异。尽管医疗保健服务有所改善,但南部网络的不良结果发生率仍然较高。
我们通过面对面访谈和病历回顾,对来自路易斯安那州西北部、阿肯色州南部和得克萨斯州东北部地区的 97 名 ESRD 患者的人口统计学指标和透析处方不依从程度进行了检查,并将其与已发表的 DOPPS 结果进行了比较。
我们发现,这个南部 ESRD 人群与美国 DOPPS 队列的整体人口统计学和透析依从性存在显著差异。大多数(95.8%)患者是非洲裔美国人,并且在透析方面的使用时间更长。大多数患者通过 4 项透析依从性测量中的 2 项被评估为不依从:29.2%的患者每月至少不参加 1 次透析治疗,86.4%的患者每月至少有 1 次将透析时间缩短 10 分钟或更长时间。这些参数被确定为 DOPPS 研究中不良结果的主要危险因素。
这个南部患者队列在透析依从性的重要指标方面与美国其他 ESRD 人群不同。这些差异可能有助于我们理解结果方面的地区差异。