Division of Anaesthesia and Intensive Care, University of Nottingham, Queen's Medical Centre, Nottingham, UK.
Anaesthesia. 2010 Apr;65 Suppl 1:22-37. doi: 10.1111/j.1365-2044.2009.06201.x.
The introduction of local anaesthesia some years after the first public demonstration of general anaesthesia not surprisingly created less excitement and interest amongst both the public and the medical profession. However, in its own way, a new revolution was happening. Local anaesthesia produced an increase in the choice of anaesthetic techniques available to practitioners and patients. In common with general anaesthesia, the choice of agents remained very limited for the first six decades, and interest in the practice of local, regional or central neuraxial blockade and the development of new techniques and drugs were hampered by perceived safety issues even as late as the second half of the 20th century. It is only in the last few years that, with an apparent renaissance in the use of local anaesthesia, the pace of development has picked up. As the use and range of techniques has increased, so has interest in solving some of the longstanding problems with the available drugs.
局部麻醉在全身麻醉首次公开演示几年后推出，这并不奇怪，它在公众和医疗界引起的兴奋和兴趣都较小。然而，它以自己的方式引发了一场新的革命。局部麻醉为从业者和患者提供了更多可供选择的麻醉技术。与全身麻醉一样，在最初的 60 年里，可供选择的药物仍然非常有限，人们对局部、区域或中枢神经轴阻滞的实践以及新技术和药物的发展的兴趣，即使到了 20 世纪后半叶，也受到安全问题的阻碍。直到最近几年，随着局部麻醉的使用明显复兴，发展的步伐才加快。随着使用和技术范围的增加，人们对解决现有药物长期存在的一些问题的兴趣也越来越大。
