Tobacco Use Prevention Section, Montana Department of Public Health and Human Services, Helena, MT 59620-2951, USA.
Nicotine Tob Res. 2010 Jun;12(6):567-73. doi: 10.1093/ntr/ntq045. Epub 2010 Apr 8.
Telephone counseling through quitlines combined with cessation medication is an effective strategy to support tobacco cessation. This study assessed the characteristics of quitline enrollees selecting varenicline (Chantix) compared with nicotine replacement therapy (NRT) medication and evaluated the cessation outcomes (7-day point prevalence) among these enrollees at 3 and 6 months after program completion.
A retrospective study analyzed demographic, tobacco use history, and abstinence outcome information of participants who enrolled in the Montana Tobacco Quit Line program and selected varenicline (n = 3,116) or NRT (n = 3,697).
Participants selecting varenicline had significantly different demographic characteristics and tobacco use histories compared with enrollees selecting NRT. In the bivariate analyses, the odds of abstinence were greater among persons using varenicline compared with NRT at 3 months (22% and 13%; odds ratio [OR] = 1.85 95% CI 1.50-2.29) and 6 months (17% and 11%; OR = 1.66 95% CI 1.23-2.24). Independently, varenicline use, increasing age, having health insurance, and a greater number of counseling sessions were associated with tobacco use abstinence at 3 months. Only increasing age and a greater number of counseling sessions were independently associated with 6-month abstinence.
Organizations providing varenicline as part of their quitline services should anticipate that participants selecting this medication have different demographic characteristics and tobacco use histories. The findings suggest that the addition of varenicline enhances 3-month abstinence rates and that the tobacco user's commitment to quit may be the most important predictor of successfully quitting.
通过戒烟热线进行电话咨询并联合使用戒烟药物是支持戒烟的有效策略。本研究评估了选择伐伦克林（Chantix）与尼古丁替代疗法（NRT）药物的戒烟热线参与者的特征，并在完成项目后 3 个月和 6 个月评估了这些参与者的戒烟结果（7 天点患病率）。
一项回顾性研究分析了参加蒙大拿州烟草戒烟热线项目并选择伐伦克林（n = 3116）或 NRT（n = 3697）的参与者的人口统计学、吸烟史和戒烟结果信息。
与选择 NRT 的参与者相比，选择伐伦克林的参与者具有明显不同的人口统计学特征和吸烟史。在双变量分析中，与使用 NRT 相比，使用伐伦克林的人在 3 个月（22%和 13%；比值比 [OR] = 1.85 95%置信区间 [CI] 1.50-2.29）和 6 个月（17%和 11%；OR = 1.66 95% CI 1.23-2.24）时更有可能戒烟。独立地，伐伦克林的使用、年龄增长、有健康保险和更多的咨询次数与 3 个月时的吸烟戒断有关。只有年龄增长和更多的咨询次数与 6 个月的戒烟独立相关。
提供伐伦克林作为其戒烟热线服务一部分的组织应该预期选择这种药物的参与者具有不同的人口统计学特征和吸烟史。研究结果表明，添加伐伦克林可提高 3 个月的戒烟率，而吸烟者戒烟的意愿可能是成功戒烟的最重要预测因素。
