用伐尼克兰治疗尼古丁咀嚼胶依赖——1 例报告。
Nicotine gum dependence treated with varenicline--a case report.
机构信息
Unité Tabac, Groupe Hospitalier Pitié-Salpétrière-Assistance Publique-Hôpitaux de Paris, 47-83 Bd de l'Hôpital, 75651 Paris Cedex 13, France.
出版信息
Nicotine Tob Res. 2010 Oct;12(10):1041-2. doi: 10.1093/ntr/ntq137. Epub 2010 Sep 9.
INTRODUCTION
The buccal absorption of nicotine replacement therapy is a part of the treatment to quit smoking. In some cases, this use could last more than six months.
METHODS AND RESULTS
We report the case of a woman, former smoker, who took nicotine gums for over five years and was treated successfully with Varenicline during six months according to the recommended posology.
DISCUSSION
Varenicline, a partial alpha 4 beta 2 nicotinic receptor agonist, could be a solution to help former smokers to stop long-term use of nicotine gums or lozenges. Further studies will be necessary to confirm this result.
引言
尼古丁替代疗法的颊部吸收是戒烟治疗的一部分。在某些情况下，这种使用可能会持续超过六个月。
方法和结果
我们报告了一位女性患者的病例，她曾经是吸烟者，使用尼古丁胶姆糖超过五年，并按照推荐的剂量方案成功接受了六个月的维拉唑尼治疗。
讨论
维拉唑尼是一种部分α 4β 2 烟碱受体激动剂，可能是帮助曾经吸烟者停止长期使用尼古丁胶姆糖或口含烟的一种解决方案。需要进一步的研究来证实这一结果。
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