New York State Department of Health, and Department of Environmental Health Sciences, Wadsworth Center, State University of New York at Albany, Empire State Plaza, PO Box 509, Albany, NY 12201-0509, USA.
Arch Environ Contam Toxicol. 2010 May;58(4):901-7. doi: 10.1007/s00244-010-9513-6. Epub 2010 Apr 9.
Organotin compounds (OTs) have been used in a wide variety of consumer products. Despite this, very few studies have reported the occurrence of OTs in house dust or exposure of humans to OTs through the ingestion of house dust. In the present study, concentrations of monobutyltin (MBT), dibutyltin (DBT), tributyltin (TBT), monooctyltin (MOT), dioctyltin (DOT), trioctyltin (TOT), diphenyltin (DPT), and triphenyltin (TPT) were measured in dust collected from 24 houses in Albany, New York, USA. In addition, a few household products, such as wallpaper, floor tile, vinyl window blinds, and handbags were analyzed for the presence of OTs. Organotins were found in all of the house dust samples analyzed, and total OT concentrations varied from 390 to 28,000 ng/g (mean +/- SD: 6700 +/- 6200; median: 5000). Relative abundances of OTs in house dust were in the order MBT >MOT >DBT >DOT >TBT. TOT, DPT, and TPT were not found in any of the samples at concentrations above their corresponding detection limits. MBT accounted for, on average, 51% of the total OT concentrations. Mean concentrations of total OTs found in house dust samples from our study were two to five times higher than concentrations that have been reported for dust samples from several European countries. Calculations indicate that dust ingestion by children account for, on average, 15-18% of the tolerable daily intake proposed by the World Health Organization (WHO). The estimated rates of OT intake by children via dust ingestion were, on average, eightfold higher than the intake rates calculated for adults. Household products, such as wallpaper, contained total OT concentrations as high as 780,000 ng/g.
有机锡化合物(OTs)已广泛应用于各种消费品中。尽管如此,很少有研究报告在家庭灰尘中发现 OTs 或人类通过摄入家庭灰尘接触 OTs。在本研究中,测量了美国纽约奥尔巴尼 24 所房屋中收集的灰尘中的单丁基锡(MBT)、二丁基锡(DBT)、三丁基锡(TBT)、单辛基锡(MOT)、二辛基锡(DOT)、三辛基锡(TOT)、二苯基锡(DPT)和三苯基锡(TPT)的浓度。此外,还分析了一些家用产品,如壁纸、地砖、乙烯基窗百叶窗和手提包,以确定是否存在 OTs。在所有分析的房屋灰尘样本中都发现了有机锡,总 OT 浓度范围为 390 至 28,000 ng/g(平均值 +/- SD:6700 +/- 6200;中位数:5000)。房屋灰尘中 OTs 的相对丰度顺序为 MBT >MOT >DBT >DOT >TBT。在任何样本中均未发现 TOT、DPT 和 TPT 的浓度超过其相应的检测限。MBT 平均占总 OT 浓度的 51%。我们的研究中从房屋灰尘样本中发现的总 OT 浓度平均值是几个欧洲国家报告的灰尘样本浓度的两到五倍。计算表明,儿童通过灰尘摄入 OT 的量平均占世界卫生组织(WHO)提出的可耐受每日摄入量的 15-18%。通过灰尘摄入摄入 OT 的儿童估计摄入率平均比成人计算的摄入率高 8 倍。家用产品,如壁纸,含有高达 780,000 ng/g 的总 OT 浓度。