用于体内靶特异性癌症成像的肽。
Peptides for in vivo target-specific cancer imaging.
机构信息
Department of Radioactive Materials. Instituto Nacional de Investigaciones Nucleares, Estado de México, Mexico.
出版信息
Mini Rev Med Chem. 2010 Jan;10(1):87-97. doi: 10.2174/138955710791112596.
PMID:20380643
Abstract
Molecular imaging comprises non-invasive monitoring of functional and spatiotemporal processes at molecular and cellular levels in living systems. Advanced imaging techniques can monitor such processes. Peptide receptors over-expressed in tumours can be targeted by peptides conjugated to radionuclides, near-infrared fluorochromes, metallic nanoparticles or quantum dots for target-specific cancer imaging.
摘要
分子影像学包括在活体内系统中对分子和细胞水平的功能和时空过程进行非侵入性监测。先进的成像技术可以监测这些过程。可以通过与放射性核素、近红外荧光染料、金属纳米粒子或量子点偶联的肽来靶向肿瘤中过表达的肽受体，用于肿瘤特异性成像。
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