Medical University of South Carolina, Charleston, SC, USA.
Am J Cardiol. 2010 Apr 15;105(8):1118-21. doi: 10.1016/j.amjcard.2009.12.014. Epub 2010 Feb 20.
The long-term efficacy and complications of cryoablation for pediatric atrioventricular nodal reentrant tachycardia (AVNRT) have not been completely defined. We performed a retrospective review of pediatric patients diagnosed with AVNRT and treated with cryoablation therapy. A total of 73 patients underwent cryoablation for AVNRT from 2003 to 2008. Of the 73 patients, 61 were included in the present study. The mean interval from initial successful ablation was 3 + or - 1 years. Of the 61 patients, 4 had documented recurrence of AVNRT after the initially successful ablation, 3 with late recurrence 1 to 2 years after ablation. Procedural complications consisting of transient atrioventricular block developed in 10 patients, and 2 patients were diagnosed with new arrhythmias after AVNRT ablation (1 with junctional ectopic tachycardia and 1 with left ventricular outflow tract tachycardia originating near the region of the atrioventricular node 3 months after ablation). In conclusion, cryoablation is a safe and effective therapy for AVNRT. Recurrences can develop late, up to 2 years after initially successful ablation.
冷冻消融治疗儿童房室结折返性心动过速（AVNRT）的长期疗效和并发症尚未完全明确。我们对 2003 年至 2008 年间接受冷冻消融治疗的 AVNRT 患儿进行了回顾性分析。共有 73 例患者接受了冷冻消融治疗 AVNRT。73 例患者中，61 例纳入本研究。初次消融成功后平均随访 3 + or - 1 年。61 例患者中，4 例消融后出现 AVNRT 复发，其中 3 例在消融后 1 至 2 年复发。10 例患者出现短暂性房室传导阻滞，2 例患者在 AVNRT 消融后出现新的心律失常（1 例交界性心动过速，1 例左室流出道起源于房室结区域附近的室性心动过速，消融后 3 个月）。总之，冷冻消融治疗 AVNRT 是一种安全有效的方法。即使在初次成功消融后 2 年内也可能发生迟发性复发。
