颞下颌关节骨关节炎中髁突吸收的量化
Quantification of condylar resorption in temporomandibular joint osteoarthritis.
作者信息
Cevidanes L H S, Hajati A-K, Paniagua B, Lim P F, Walker D G, Palconet G, Nackley A G, Styner M, Ludlow J B, Zhu H, Phillips C
机构信息
Department of Orthodontics, University of North Carolina School of Dentistry, Chapel Hill, North Carolina 27599, USA.
出版信息
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Jul;110(1):110-7. doi: 10.1016/j.tripleo.2010.01.008. Epub 2010 Apr 9.
OBJECTIVE
This study was performed to determine the condylar morphologic variation of osteoarthritic (OA) and asymptomatic temporomandibular joints (TMJs) and to determine its correlation with pain intensity and duration.
STUDY DESIGN
Three-dimensional surface models of mandibular condyles were constructed from cone-beam computerized tomography images of 29 female patients with TMJ OA (Research Diagnostic Criteria for Temporomandibular Disorders group III) and 36 female asymptomatic subjects. Shape correspondence was used to localize and quantify the condylar morphology. Statistical analysis was performed with multivariate analysis of covariance analysis, using Hotelling T(2) metric based on covariance matrices, and Pearson correlation.
RESULTS
The OA condylar morphology was statistically significantly different from the asymptomatic condyles (P < .05). Three-dimensional morphologic variation of the OA condyles was significantly correlated with pain intensity and duration.
CONCLUSION
Three-dimensional quantification of condylar morphology revealed profound differences between OA and asymptomatic condyles, and the extent of the resorptive changes paralleled pain severity and duration.
目的
本研究旨在确定骨关节炎（OA）和无症状颞下颌关节（TMJ）的髁突形态学变化，并确定其与疼痛强度和持续时间的相关性。
研究设计
从29名患有颞下颌关节OA的女性患者（颞下颌关节紊乱研究诊断标准III组）和36名无症状女性受试者的锥形束计算机断层扫描图像构建下颌髁突的三维表面模型。使用形状对应来定位和量化髁突形态。基于协方差矩阵，使用Hotelling T(2)度量进行多变量协方差分析和Pearson相关性统计分析。
结果
OA髁突形态与无症状髁突在统计学上有显著差异（P <.05）。OA髁突的三维形态变化与疼痛强度和持续时间显著相关。
结论
髁突形态的三维量化显示OA髁突与无症状髁突之间存在显著差异，吸收变化的程度与疼痛严重程度和持续时间平行。
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