Wynn A H, Crawford M A, Doyle W, Wynn S W
Institute of Brain Chemistry and Human Nutrition, Hackney Hospital, London.
Nutr Health. 1991;7(2):69-88. doi: 10.1177/026010609100700203.
A causal connection between maternal nutrient intake and birth outcome is not universally accepted. In this paper further empirical support is provided, particularly in relation to the impact of maternal nutrition around the time of conception or very early in pregnancy. It is argued that the hypothesis that maternal nutrition has no connection with birthweight is very easily refuted. It is suggested that there should be a new category of recommended dietary allowances; "women in anticipation of pregnancy". The diet of 513 pregnant London women were recorded for 7 days during the first trimester of their pregnancy. Birthweight and nutrient intakes were found to be significantly correlated but only over the lower half of the birthweight range. The optimum birthweight range with the lowest perinatal and infant mortalities is 3,500-4,500 g and it is suggested that the nutrient intake of th 165 women who had babies in this optimum weight range provide tentative values for nutrient intake recommendations in anticipation of pregnancy, but are not claimed to be representative. The need for adjustments of recommendations for the individual, for example for a low body mass index, is discussed. A body mass index of 24 kg/m2 is recommended based on the median of the 165 women.
母体营养摄入与出生结局之间的因果关系并未得到普遍认可。本文提供了进一步的实证支持,特别是关于受孕时或怀孕早期母体营养的影响。有人认为,母体营养与出生体重无关的假设很容易被反驳。建议设立一类新的膳食推荐摄入量;“备孕女性”。对513名伦敦孕妇在其怀孕头三个月的7天饮食进行了记录。发现出生体重与营养摄入量显著相关,但仅在出生体重范围的下半部分如此。围产期和婴儿死亡率最低的最佳出生体重范围是3500 - 4500克,建议对在这个最佳体重范围内分娩的165名女性的营养摄入量提供备孕时营养摄入推荐的暂定数值,但并不声称具有代表性。讨论了针对个体调整推荐量的必要性,例如针对低体重指数的情况。根据这165名女性的中位数,建议体重指数为24 kg/m²。