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髂股静脉汇合处双侧支架置入术。

Bilateral stenting at the iliocaval confluence.

机构信息

River Oaks Hospital, Flowood, Miss, USA.

出版信息

J Vasc Surg. 2010 Jun;51(6):1457-66. doi: 10.1016/j.jvs.2010.01.056. Epub 2010 Apr 10.

Abstract

OBJECTIVE

This study describes three techniques of stent placement at the iliocaval confluence for chronic nonmalignant obstruction and its stent-related outcome.

METHODS

From 1997 to 2008, 115 patients (230 limbs) underwent bilateral stenting for iliocaval obstruction. All limbs were CEAP classified using clinical examination and duplex ultrasound study. Three techniques were compared: placement of two stents side by side in a "double-barrel" (group DB, n = 39); inverted Y stenting through a fenestra (window) created through the side braiding of a stent placed previously across the iliocaval confluence (group iY, n = 38); apposition of a stent as close as possible to a stent previously placed across the iliocaval confluence, leaving a small area unsupported between the stents (group A, n = 38). Patency was assessed with venography and duplex ultrasound imaging. Cumulative patency curves were calculated.

RESULT

Median age was 54 years (range, 14-76 years); female/male ratio was 2.8:1. Obstructions were primary in 141 limbs and postthrombotic in 89, and 29 required recanalization of occlusions. The C(4-6) rate and ratio of limbs with postthrombotic obstruction were significantly higher in group iY vs group DB (49% and 32% [P = .049]; 47% and 28% [P = .022], respectively). The median follow-up was 12 months (range, 1-108 months) in 107 patients (93%). The overall primary, assisted primary, and secondary patency rates at 4 years were 61%, 92%, and 98%, respectively. The distribution of occluded stent systems (n = 4) and frequency of reinterventions (n = 29) were reflected in the primary and secondary patency rates for groups A, DB, and iY at 4 years (77% and 100%, 73% and 100%, and 41% and 90%, respectively). The frequency of reinterventions was significantly lower in group DB vs groups A and iY (8%, 32%, and 37%, respectively; P < .01).

CONCLUSION

Chronic iliocaval confluence obstruction is best managed by double-barrel stenting when feasible. The apposition technique requires a high reintervention rate owing to restenosis of the unsupported segment. The secondary stent patency appears to be less in limbs with postthrombotic occlusion. Primary stent patency of nonocclusive obstruction was inferior in group iY regardless of etiology of obstruction. However, inverted Y fenestration is the only choice in delayed contralateral stenting or when the inferior vena cava is extensively involved. There is no optimal solution to the treatment of the iliocaval confluence presently, and the choice of technique is decided by the extent, site, and type of obstruction.

摘要

目的

本研究描述了在髂静脉汇合处放置支架治疗慢性非恶性梗阻的三种技术及其支架相关的结果。

方法

1997 年至 2008 年间,115 例(230 条肢体)患者因髂静脉阻塞而行双侧支架置入术。所有肢体均采用临床检查和双功能超声检查进行 CEAP 分类。比较了三种技术:并排放置两个支架形成“双腔”(DB 组,n = 39);通过先前穿过髂静脉汇合处的支架的侧编织形成的倒 Y 支架(iY 组,n = 38);将支架尽可能靠近先前放置在髂静脉汇合处的支架,在支架之间留下一小段未支撑的区域(A 组,n = 38)。通过静脉造影和双功能超声成像评估通畅性。计算累积通畅率曲线。

结果

中位年龄为 54 岁(范围,14-76 岁);男女比例为 2.8:1。141 条肢体原发性阻塞,89 条肢体血栓后阻塞,29 条肢体需要再通阻塞。iY 组的 C(4-6)率和血栓后阻塞肢体的比例明显高于 DB 组(49%和 32%[P =.049];47%和 28%[P =.022])。107 例患者(93%)中位随访时间为 12 个月(范围,1-108 个月)。107 例患者(93%)的 4 年总体原发性、辅助原发性和继发性通畅率分别为 61%、92%和 98%。4 年时 A 组、DB 组和 iY 组的闭塞支架系统分布(n = 4)和再介入频率(n = 29)反映了原发性和继发性通畅率(分别为 77%和 100%、73%和 100%和 41%和 90%)。与 A 组和 iY 组相比,DB 组的再介入频率显著降低(8%、32%和 37%;P <.01)。

结论

在可行的情况下,双腔支架置入术是治疗髂静脉汇合处慢性梗阻的最佳方法。由于未支撑段的再狭窄,贴壁技术需要较高的再介入率。血栓后阻塞肢体的二级支架通畅率似乎较低。无论阻塞的病因如何,iY 组的原发性支架通畅率均较差。然而,倒 Y 型开窗术是对侧延迟支架置入或下腔静脉广泛受累的唯一选择。目前,治疗髂静脉汇合处没有最佳的解决方案,技术的选择取决于梗阻的范围、部位和类型。

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