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[瓦加杜古(布基纳法索)的风湿性疾病和血红蛋白病]

[Rheumatologic diseases and haemoglobinopathies in Ouagadougou (Burkina Faso)].

作者信息

Ouédraogo D-D, Nacoulma E W C, Kafando E, Ouédraogo A, Tiéno H, Koulidiaty J, Drabo J Y

机构信息

Service de médecine interne, centre hospitalier universitaire Yalgado-Ouédraogo (CHU-YO), Ouagadougou, Burkina Faso.

出版信息

Bull Soc Pathol Exot. 2010 May;103(2):80-3. doi: 10.1007/s13149-010-0052-1. Epub 2010 Apr 13.

Abstract

The purpose of this study is the prevalence of the rheumatologic complications in the sickle cell disease and the associations between haemoglobinopathies and rheumatologic affections. It is a retrospective study from 29 February 2006 to 28 March 2008 conducted in the Internal Department of the University Hospital Yalgado-Ouédraogo. All patients received in the period of study and having an electrophoresis of haemoglobin realized in alkaline pH were included. These patients came from hematologic consultation. Two hundred and seventy-seven patients out of 1451 were included: 142 patients (51.30%) had haemoglobinopathies, including 21 (7.60%) with composite sickle cell disease SC and 17 patients (6.13%) had aseptic necrosis of the femoral head including 7 with haemoglobin SC. The other rheumatologic affections did not have a semiological particularity related to the type of haemoglobin. The prevalence of patients who have haemoglobinopathies is important in rheumatologic practice. The sickle cell disease is strongly associated to osteonecrosis.

摘要

本研究的目的是了解镰状细胞病中风湿性并发症的患病率以及血红蛋白病与风湿性疾病之间的关联。这是一项于2006年2月29日至2008年3月28日在亚尔加杜-韦德拉奥果大学医院内科进行的回顾性研究。纳入了在研究期间接受治疗且进行了碱性pH值血红蛋白电泳的所有患者。这些患者来自血液科门诊。1451名患者中有277名被纳入:142名患者(51.30%)患有血红蛋白病,其中21名(7.60%)患有复合型镰状细胞病SC,17名患者(6.13%)患有股骨头无菌性坏死,其中7名患有血红蛋白SC。其他风湿性疾病在症状学上与血红蛋白类型无关。血红蛋白病患者的患病率在风湿性疾病实践中很重要。镰状细胞病与骨坏死密切相关。

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