Munck Anne
CF Center, University Hospital Robert Debré, AP-HP 48, bd Serurier 75019 Paris, France.
Expert Rev Respir Med. 2010 Feb;4(1):47-56. doi: 10.1586/ers.09.66.
Nutritional status is strongly associated with pulmonary function and survival in cystic fibrosis patients. Attainment of a normal growth pattern in childhood and maintenance of adequate nutritional status in adulthood represent major goals of multidisciplinary cystic fibrosis centers. International guidelines on energy intake requirements, pancreatic enzyme-replacement therapy and fat-soluble vitamin supplementation are of utmost importance in daily practice. The present review summarizes the most up-to-date information on early nutritional management in newly diagnosed patients and evaluates the benefits of aggressive nutritional support, assessment of nutritional status, recommendations for nutrition-related management in pancreatic-insufficient patients and the possible therapeutic impact of fat intake modulation upon inflammatory status.
营养状况与囊性纤维化患者的肺功能及生存密切相关。在儿童期实现正常生长模式并在成年期维持充足的营养状况是多学科囊性纤维化中心的主要目标。关于能量摄入需求、胰酶替代疗法和脂溶性维生素补充的国际指南在日常实践中至关重要。本综述总结了新诊断患者早期营养管理的最新信息，并评估了积极营养支持的益处、营养状况评估、胰腺功能不全患者营养相关管理的建议以及脂肪摄入调节对炎症状态可能产生的治疗影响。
