Galle P C, McCool J A, Elsner C W
Obstet Gynecol. 1978 Mar;51(3):359-64. doi: 10.1097/00006250-197803000-00023.
Arrhenoblastoma is a rare complication of pregnancy. A case of fatal nonvirilizing arrhenoblastoma in a pregnant adolescent, the third such case to appear in the literature, is discussed. Fifteen cases of arrhenoblastoma in pregnancy that have appeared in the recent literature are reviewed; 87% of these tumors were virilizing. When virilization is absent the diagnosis is difficult. Among the more common presenting symptoms are weight loss, nausea and vomiting, abdominal pain, and a palpable abdominal mass. Arrhenoblastoma occurring during pregnancy has a 31% maternal mortality, 44% rate of malignancy, and a 50% perinatal mortality.
卵巢支持间质细胞瘤是妊娠的一种罕见并发症。本文讨论了一例发生在青春期孕妇的致命性非男性化卵巢支持间质细胞瘤，这是文献中出现的第三例此类病例。回顾了近期文献中报道的15例妊娠合并卵巢支持间质细胞瘤病例；其中87%的肿瘤具有男性化表现。当不存在男性化表现时，诊断较为困难。较常见的症状包括体重减轻、恶心、呕吐、腹痛以及可触及的腹部肿块。妊娠期发生的卵巢支持间质细胞瘤产妇死亡率为31%，恶性率为44%，围产期死亡率为50%。
