Guy's & St Thomas' Hospitals NHS Trust, Cardiology, London, UK.
J Sex Med. 2010 Apr;7(4 Pt 2):1608-26. doi: 10.1111/j.1743-6109.2010.01779.x.
Erectile dysfunction (ED) is common and considered to be predominantly of vascular origin.
To evaluate the link between ED and coronary artery disease (CAD) and provide a consensus report regarding evaluation and management.
A committee of eight experts from six countries was convened to review the worldwide literature concerning ED and CAD and provide a guideline for management.
Expert opinion was based on grading the evidence-based medical literature, widespread internal committee discussion, public presentation, and debate.
ED and CAD frequently coexist. Between 50-70% of men with CAD have ED. ED can arise before CAD is symptomatic with a time window of 3-5 years. ED and CAD share the same risk factors, and endothelial dysfunction is the common denominator. Treating ED in cardiac patients is safe, provided that their risks are properly evaluated.
ED is a marker for silent CAD that needs to be excluded. Men with CAD frequently have ED that can be treated safely following guidelines.
勃起功能障碍(ED)很常见,被认为主要源于血管问题。
评估 ED 与冠状动脉疾病(CAD)之间的联系,并提供有关评估和管理的共识报告。
从六个国家召集了一个由八名专家组成的委员会,审查了全球范围内有关 ED 和 CAD 的文献,并制定了管理指南。
专家意见基于对循证医学文献的分级、广泛的内部委员会讨论、公开演示和辩论。
ED 和 CAD 经常同时存在。在患有 CAD 的男性中,有 50%-70%患有 ED。在 CAD 出现症状前 3-5 年内,ED 可能已经出现。ED 和 CAD 具有相同的危险因素,内皮功能障碍是共同的发病机制。对心脏患者进行 ED 治疗是安全的,只要对其风险进行适当评估。
ED 是无症状 CAD 的标志物,需要排除。患有 CAD 的男性经常会出现 ED,可以根据指南安全地进行治疗。