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肛门狭窄治疗中房式推进皮瓣、菱形皮瓣与 Y-V 成形术的对比研究:一项前瞻性随机研究。

Comparative study of the house advancement flap, rhomboid flap, and y-v anoplasty in treatment of anal stenosis: a prospective randomized study.

机构信息

Department of General Surgery, Colorectal Surgery Unit, Mansoura University, Mansoura, Egypt.

出版信息

Dis Colon Rectum. 2010 May;53(5):790-7. doi: 10.1007/DCR.0b013e3181d3205a.

Abstract

PURPOSE

Anal stenosis represents a technical challenge for surgical management. We compared the effects of house flap, rhomboid flap, and Y-V anoplasty procedures in a randomized study in patients with anal stenosis.

METHODS

Consecutive patients treated for anal stenosis at our institution were evaluated for inclusion. Participants were randomly allocated to receive house flap, rhomboid flap, or Y-V anoplasty. Follow-up visits were after 1 week, 1 month, 6 months, and 1 year. Study variables included caliber of the anal canal (measured with a conical calibrator), clinical improvement, patient satisfaction (visual analog scale), incontinence (Pescatori incontinence scale), and quality of life (GI Quality of Life Inventory).

RESULTS

: Sixty patients with anal stenosis were randomized and completed the study. Operative time was 62 +/- 10 minutes for house flap, 44 +/- 13 minutes for rhomboid flap, and 35 +/- 9 minutes for Y-V anoplasty (P = .042). At 1 year, anal caliber was 23.9 +/- 2.33 mm for house flap, 18.1 +/- 2.05 mm for rhomboid flap, and 16.4 +/- 2.05 mm for Y-V anoplasty (P = .04), with a highly significant increase for the house flap (P = .001). The groups differed significantly regarding clinical improvement at 1 month (95% for house flap, 80% for rhomboid flap, and 65% for Y-V anoplasty, P = .01) and differences persisted at 1 year. Significant differences were seen among groups at 1 year in GI Quality of Life Inventory scores (P = .03), with significant improvement only for the house flap (P = .01).

CONCLUSION

Anal stenosis can be effectively managed with the house flap procedure, with the sole disadvantage of longer operative time. Although all 3 procedures are simple and easy to perform, the house flap appears to produce the greatest clinical improvement, patient satisfaction, and improvement in quality of life, with the fewest complications.

摘要

目的

肛门狭窄是外科治疗的技术难题。我们在一项随机研究中比较了肛门狭窄患者行肛门皮瓣成形术、菱形皮瓣成形术和 Y-V 成形术的效果。

方法

评估我院收治的肛门狭窄患者,纳入连续患者。参与者被随机分配接受肛门皮瓣成形术、菱形皮瓣成形术或 Y-V 成形术。随访时间为术后 1 周、1 个月、6 个月和 1 年。研究变量包括肛管口径(用锥形校准器测量)、临床改善、患者满意度(视觉模拟评分)、失禁(Pescatori 失禁评分)和生活质量(GI 生活质量量表)。

结果

60 例肛门狭窄患者随机分组并完成研究。肛门皮瓣成形术的手术时间为 62±10 分钟,菱形皮瓣成形术为 44±13 分钟,Y-V 成形术为 35±9 分钟(P=0.042)。1 年后,肛门皮瓣成形术的肛管口径为 23.9±2.33mm,菱形皮瓣成形术为 18.1±2.05mm,Y-V 成形术为 16.4±2.05mm(P=0.04),肛门皮瓣成形术有显著增加(P=0.001)。组间 1 个月时临床改善差异显著(肛门皮瓣成形术 95%,菱形皮瓣成形术 80%,Y-V 成形术 65%,P=0.01),1 年后差异仍存在。1 年后,3 组在 GI 生活质量量表评分方面存在显著差异(P=0.03),仅肛门皮瓣成形术有显著改善(P=0.01)。

结论

肛门皮瓣成形术可有效治疗肛门狭窄,唯一缺点是手术时间较长。虽然这 3 种手术都简单易行,但肛门皮瓣成形术似乎能产生最大的临床改善、患者满意度和生活质量改善,并发症最少。

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