Department of Internal Medicine, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland.
Infection. 2010 Aug;38(4):331-4. doi: 10.1007/s15010-010-0024-1.
A 70 year-old female patient presented with fever, nausea and dyspnea. She had been receiving immunosuppressive therapy with methotrexate and prednisone for large-vessel vasculitis. The patient was shown to have coexistent Pneumocystis jiroveci pneumonia and primary cytomegalovirus (CMV) infection with presumed CMV pneumonitis and colitis. To our knowledge, this is the first case report on the occurrence of combined primary cytomegalovirus and Pneumocystis jiroveci infection in a patient with vasculitis. It illustrates the importance of being aware of the possibility of combined opportunistic infections in patients with rheumatologic diseases.
一位 70 岁女性患者因发热、恶心和呼吸困难就诊。她因大血管血管炎一直在接受甲氨蝶呤和泼尼松的免疫抑制治疗。患者被发现同时患有卡氏肺孢子虫肺炎和原发性巨细胞病毒(CMV)感染,推测存在 CMV 肺炎和结肠炎。据我们所知,这是首例报告在血管炎患者中同时发生原发性巨细胞病毒和卡氏肺孢子虫感染的病例。它说明了在风湿性疾病患者中意识到合并机会性感染可能性的重要性。