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神经源性尿失禁患儿行吊带术而不做膀胱颈加强术后逼尿肌顺应性的变化。

Detrusor compliance changes after bladder neck sling without augmentation in children with neurogenic urinary incontinence.

机构信息

Pediatric Urology Section, University of Texas Southwestern Medical Center and Children's Medical Center, Dallas, Texas 75207, USA.

出版信息

J Urol. 2010 Jun;183(6):2361-6. doi: 10.1016/j.juro.2010.02.029. Epub 2010 Apr 18.

Abstract

PURPOSE

We reviewed preoperative, and initial and final postoperative urodynamic testing in consecutive children undergoing bladder neck sling without augmentation for neurogenic urinary incontinence to determine if progressive loss of compliance occurs.

MATERIALS AND METHODS

We assessed consecutive patients with neurogenic outlet incompetence who underwent 360-degree tight fascial wrap around the bladder neck with appendicovesicostomy but no augmentation. This population comprised all patients undergoing outlet surgery between 2002 and 2007. Inclusion criteria were initial urodynamic test within 1 year postoperatively and final urodynamic test at least 18 months postoperatively.

RESULTS

A total of 26 patients met inclusion criteria. Most patients (73%) had an acontractile bladder with detrusor pressures less than 25 cm H(2)O preoperatively. Initial postoperative urodynamic test at a mean of 7 months was most predictive of subsequent urodynamic findings. Eight patients (31%) had increased detrusor pressures and/or uninhibited contractions postoperatively. Six patients increased anticholinergic therapy dose. At a mean of 39 months urodynamic patterns were either stable or improved in all patients.

CONCLUSIONS

Progressive compliance loss was not observed after bladder neck sling without augmentation. Postoperative increases in detrusor pressure and/or uninhibited contractions within 1 year postoperatively should prompt review of anticholinergic therapy rather than enterocystoplasty.

摘要

目的

我们回顾了连续接受无增强膀胱颈吊带术治疗神经源性尿失禁的儿童的术前、初始和最终术后尿动力学检查结果,以确定是否存在顺应性逐渐丧失的情况。

材料和方法

我们评估了连续患有神经源性出口功能不全的患者,这些患者接受了 360 度环绕膀胱颈的紧密筋膜包裹术和阑尾膀胱造口术,但未进行增强。该人群包括所有在 2002 年至 2007 年间接受出口手术的患者。纳入标准为术后 1 年内进行初始尿动力学检查,且术后至少 18 个月进行最终尿动力学检查。

结果

共有 26 名患者符合纳入标准。大多数患者(73%)术前膀胱呈无收缩状态,逼尿肌压力低于 25cmH2O。术后 7 个月的初始尿动力学检查最能预测随后的尿动力学发现。8 名患者(31%)术后出现逼尿肌压力升高和/或无抑制性收缩。6 名患者增加了抗胆碱能药物的剂量。在平均 39 个月时,所有患者的尿动力学模式均保持稳定或改善。

结论

在未进行增强的膀胱颈吊带术后未观察到顺应性逐渐丧失。术后 1 年内逼尿肌压力升高和/或无抑制性收缩应促使重新评估抗胆碱能药物治疗,而不是进行肠膀胱扩大术。

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