Snodgrass Warren, Keefover-Hicks Amy, Prieto Juan, Bush Nicol, Adams Richard
Pediatric Urology Section, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75207, USA.
J Urol. 2009 Jun;181(6):2709-14; discussion 2714-6. doi: 10.1016/j.juro.2009.02.035. Epub 2009 Apr 17.
We compared 2 cohorts of children with neurogenic urinary incontinence undergoing bladder neck sling with and without augmentation to determine relative continence outcomes, catheterization intervals, anticholinergic requirements and health related quality of life improvement as perceived by the patients and their parents.
Consecutive patients followed through our spina bifida program underwent a structured postoperative interview by a research nurse to assess continence, interval between catheterizations and anticholinergic use. In addition, the child and parent together answered a health related quality of life satisfaction survey to determine the impact of surgery from their perspectives.
There were 18 patients undergoing sling with augmentation and 23 with sling alone. Overall improved continence rate was 83%, with no difference between outcomes in patients with vs without augmentation. However, the interval between catheterizations was longer and the use of anticholinergics was less following augmentation. Nevertheless, health related quality of life responses differed significantly in only 1 area, independent care, with both cohorts reporting similarly improved overall health, and increased ability to participate in social and leisure activities.
We directly compared results in patients undergoing slings with and without augmentation. Both procedures were similarly successful in achieving improved continence, with patients undergoing augmentation having a longer interval between catheterization and requiring fewer anticholinergics. However, health related quality of life responses revealed that both cohorts were similarly satisfied with the outcomes.
我们比较了两组患有神经源性尿失禁的儿童,一组接受膀胱颈悬吊术并同时进行膀胱扩大术,另一组仅接受膀胱颈悬吊术,以确定相对的控尿结果、导尿间隔时间、抗胆碱能药物的使用需求以及患者及其父母所感知的与健康相关的生活质量改善情况。
通过我们的脊柱裂项目随访的连续患者接受了研究护士的结构化术后访谈,以评估控尿情况、导尿间隔时间和抗胆碱能药物的使用情况。此外,儿童及其父母共同回答了一项与健康相关的生活质量满意度调查,以从他们的角度确定手术的影响。
有18例患者接受了悬吊术并同时进行膀胱扩大术,23例仅接受悬吊术。总体控尿改善率为83%,接受膀胱扩大术与未接受膀胱扩大术的患者结果无差异。然而,膀胱扩大术后导尿间隔时间更长,抗胆碱能药物的使用更少。尽管如此,与健康相关的生活质量反应仅在一个方面存在显著差异,即独立护理方面,两组患者报告的总体健康状况均有类似改善,参与社交和休闲活动的能力也有所提高。
我们直接比较了接受悬吊术并同时进行膀胱扩大术与仅接受悬吊术的患者的结果。两种手术在实现控尿改善方面同样成功,接受膀胱扩大术的患者导尿间隔时间更长,所需抗胆碱能药物更少。然而,与健康相关的生活质量反应显示,两组患者对结果的满意度相似。