Valencia University, Department of Stomatology, University General Hospital, Valencia, Spain.
Oral Oncol. 2010 Jun;46(6):414-7. doi: 10.1016/j.oraloncology.2010.03.009. Epub 2010 Apr 18.
Oral squamous cell carcinoma (OSCC) is a well-known malignancy that accounts for more than 90% of all oral cancers. In this article we will perform a brief review of its clinical characteristics and the differential diagnosis. Regarding symptoms, pain is the most frequent presentation and the tongue and the floor of the mouth have the highest occurrence. OSCC in its initial stages shows an erytholeukoplastic area without symptoms but in advanced stages there are ulcers and lumps with irregular margins which are rigid to touch. The different diagnosis should be established with other oral malignant diseases such as lymphomas, sarcomas and metastasis, which have rapid growth rates as opposed to the typical OSCC.
口腔鳞状细胞癌（OSCC）是一种众所周知的恶性肿瘤，占所有口腔癌的 90%以上。在本文中，我们将简要回顾其临床特征和鉴别诊断。就症状而言，疼痛是最常见的表现，而舌和口底的发病率最高。OSCC 在早期阶段表现为无明显症状的红斑样区域，但在晚期则出现溃疡和肿块，边缘不规则，触摸时质地坚硬。鉴别诊断应与其他口腔恶性疾病如淋巴瘤、肉瘤和转移瘤相鉴别，这些疾病的生长速度与典型的 OSCC 相反。
