Centre of Advanced Study in Botany, Banaras Hindu University, Varanasi, India.
Mycopathologia. 2010 Sep;170(3):195-202. doi: 10.1007/s11046-010-9311-8. Epub 2010 Apr 17.
Essential oils extracted from Citrus reticulata and Cymbopogon citratus were tested in vitro against the toxigenic strain of Aspergillus flavus, isolated from the tuberous roots of Asparagus racemosus, used in preparation of herbal drugs. The essential oils completely inhibited the growth of A. flavus at 750 ppm and also exhibited a broad fungitoxic spectrum against nine additional fungi isolated from the roots. Citrus reticulata and Cymbopogon citratus essential oils completely inhibited aflatoxin B(1) production at 750 and 500 ppm, respectively. During in vivo investigation, the incidence of fungi and aflatoxin B(1) production decreased considerably in essential oil-treated root samples. The findings thus indicate possible exploitation of the essential oils as effective inhibitor of aflatoxin B(1) production and as post-harvest fungitoxicant of traditionally used plant origin for the control of storage fungi. These essential oils may be recommended as plant-based antifungals as well as aflatoxin B(1) suppressors in post-harvest processing of herbal samples.
从天门冬块根中分离出的产毒黄曲霉（Aspergillus flavus）菌株，用其对从天门冬块根中分离出的九种真菌进行了体外抑菌实验，结果表明从柑橘和香茅中提取的精油在 750ppm 时完全抑制了黄曲霉的生长，并且对另外九种真菌也具有广谱的抑菌活性。柑橘和香茅精油在 750ppm 和 500ppm 时完全抑制了黄曲霉毒素 B1 的产生。在体内研究中，用精油处理的块根样本中真菌的发生率和黄曲霉毒素 B1 的产生量明显降低。因此，这些精油可能被开发为有效的黄曲霉毒素 B1 抑制剂，以及传统植物来源的收获后真菌杀菌剂，以控制贮藏真菌。这些精油可作为植物性抗真菌剂以及中草药样品收获后处理的黄曲霉毒素 B1 抑制剂。
