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钴铬合金与不锈钢药物洗脱支架扩张的血管内超声评估。

Intravascular ultrasound assessment of cobalt chromium versus stainless steel drug-eluting stent expansion.

机构信息

Cardiovascular Research Foundation, Columbia University Medical Center-New York Presbyterian Hospital, New York, NY, USA.

出版信息

Am J Cardiol. 2010 May 1;105(9):1272-5. doi: 10.1016/j.amjcard.2009.12.042.

Abstract

It is not clear whether the thin struts and different alloy of a cobalt chromium stent will cause greater acute stent recoil compared to conventional stainless steel stents. We used postintervention intravascular ultrasound (IVUS) examinations to study 99 patients with 116 stented lesions: 61 Xience/Promus stents (cobalt chromium stent group) and 27 Taxus Liberté and 28 Cypher stents (stainless steel stent group). The IVUS images were obtained before and immediately after stent implantation with only the stent-delivery balloon. The ratio of the IVUS-measured to manufacturer-predicted stent diameter and area was the measure of acute stent recoil and expansion. The baseline patient characteristics, lesion morphology, and procedural details were comparable between the 2 groups. The ratio of the IVUS-measured to manufacturer-predicted stent diameter and area was 0.74 versus 0.73 (p = 0.57) and 0.63 versus 0.63 (p = 0.69), respectively, for the cobalt chromium and stainless steel stents. In conclusion, the acute performance of Xience/Promus was similar to that of previous stainless steel stents, and the thinner cobalt chromium metallic platform did not compromise the radial strength of the stent.

摘要

目前尚不清楚与传统的不锈钢支架相比,钴铬支架较细的支架支柱和不同的合金是否会导致更大的急性支架回缩。我们使用血管内超声(IVUS)检查对 99 例 116 个支架病变患者进行了研究:61 个 Xience/Promus 支架(钴铬支架组)和 27 个 Taxus Liberté 和 28 个 Cypher 支架(不锈钢支架组)。在仅使用支架输送球囊进行支架置入前后获得 IVUS 图像。IVUS 测量的支架直径与制造商预测的支架直径之比和支架面积与制造商预测的支架面积之比是急性支架回缩和扩张的衡量指标。两组患者的基线特征、病变形态和手术细节相似。IVUS 测量的支架直径与制造商预测的支架直径之比和支架面积与制造商预测的支架面积之比分别为 0.74 比 0.73(p = 0.57)和 0.63 比 0.63(p = 0.69),钴铬支架和不锈钢支架之间无显著差异。总之,Xience/Promus 的急性性能与以前的不锈钢支架相似,较薄的钴铬金属平台并未损害支架的径向强度。

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