The Research Clinic for Functional Disorders and Psychosomatics, Aarhus University Hospital, 8000 Aarhus, Denmark.
J Psychosom Res. 2010 May;68(5):415-26. doi: 10.1016/j.jpsychores.2010.02.004.
In order to clarify the classification of physical complaints not attributable to verifiable, conventionally defined diseases, a new diagnosis of bodily distress syndrome was introduced. The aim of this study was to test if patients diagnosed with one of six different functional somatic syndromes or a DSM-IV somatoform disorder characterized by physical symptoms were captured by the new diagnosis.
A stratified sample of 978 consecutive patients from neurological (n=120) and medical (n=157) departments and from primary care (n=701) was examined applying post-hoc diagnoses based on the Schedules for Clinical Assessment in Neuropsychiatry diagnostic instrument. Diagnoses were assigned only to clinically relevant cases, i.e., patients with impairing illness.
Bodily distress syndrome included all patients with fibromyalgia (n=58); chronic fatigue syndrome (n=54) and hyperventilation syndrome (n=49); 98% of those with irritable bowel syndrome (n=43); and at least 90% of patients with noncardiac chest pain (n=129), pain syndrome (n=130), or any somatoform disorder (n=178). The overall agreement of bodily distress syndrome with any of these diagnostic categories was 95% (95% CI 93.1-96.0; kappa 0.86, P<.0001). Symptom profiles of bodily distress syndrome organ subtypes were similar to those of the corresponding functional somatic syndromes with diagnostic agreement ranging from 90% to 95%.
Bodily distress syndrome seem to cover most of the relevant "somatoform" or "functional" syndromes presenting with physical symptoms, not explained by well-recognized medical illness, thereby offering a common ground for the understanding of functional somatic symptoms. This may help unifying research efforts across medical disciplines and facilitate delivery of evidence-based care.
为了明确无法归因于可核实的、传统定义的疾病的躯体抱怨的分类,引入了一种新的躯体不适综合征诊断。本研究的目的是检验诊断为六种不同的功能性躯体综合征之一或一种以躯体症状为特征的 DSM-IV 躯体形式障碍的患者是否被新诊断所涵盖。
对来自神经科(n=120)、内科(n=157)和初级保健科(n=701)的连续患者进行分层抽样,应用基于精神科临床评估计划诊断工具的事后诊断进行检查。仅对有临床意义的病例,即有损害疾病的患者进行诊断。
躯体不适综合征包括所有纤维肌痛(n=58)、慢性疲劳综合征(n=54)和过度通气综合征(n=49)患者;98%的肠易激综合征(n=43)患者;至少 90%的非心因性胸痛(n=129)、疼痛综合征(n=130)或任何躯体形式障碍(n=178)患者。躯体不适综合征与任何这些诊断类别的总体一致性为 95%(95%置信区间 93.1-96.0;kappa 值 0.86,P<.0001)。躯体不适综合征器官亚型的症状谱与相应的功能性躯体综合征相似,诊断一致性在 90%至 95%之间。
躯体不适综合征似乎涵盖了大多数具有躯体症状、无法用公认的医学疾病解释的相关“躯体形式”或“功能性”综合征,从而为理解功能性躯体症状提供了一个共同的基础。这可能有助于跨医学学科统一研究工作,并促进提供基于证据的护理。