National Capital Poison Center, Washington, DC 20016, USA.
Pediatrics. 2010 May;125(5):906-13. doi: 10.1542/peds.2009-2080. Epub 2010 Apr 19.
To demonstrate the value of poison control data as an adjunct to national drug abuse surveys and a source of data to inform and focus prevention efforts.
National Poison Data System (NPDS) data are collected and compiled in real time by the 60 US poison centers as callers seek guidance for poison exposures. Demographic, geographic, product, outcome, and treatment-site data for the 35453 inhalant cases reported between 1993 and 2008 were analyzed.
The prevalence of inhalant cases reported to US poison control centers decreased 33% from 1993 to 2008. Prevalence was highest among children aged 12 to 17 years and peaked in 14-year-olds. In contrast to national survey data showing nearly equal use of inhalants by both genders, 73.5% of NPDS inhalant cases occurred in boys, which suggests that boys may pursue riskier usage behaviors. Most cases (67.8%) were managed in health care facilities. More than 3400 different products were reported. Propellants, gasoline, and paint were the most frequent product categories. Propellants were the only product category that substantially increased over time. Butane, propane, and air fresheners had the highest fatality rates. Prevalence for all inhalants was highest in western mountain states and West Virginia, but geographic distribution varied according to product type. Gasoline was a proportionately greater problem for younger children; propellants were an issue for older children.
NPDS should be used to monitor inhalant abuse because it provides unique, timely, and clinically useful information on medical outcomes experienced by users, includes detailed product information (brand and formulation), and can potentially be used to identify real-time demographic, geographic, and product trends. Focusing inhalant prevention efforts on the most hazardous products and most seriously affected users may improve and facilitate strategic prevention, enabling interventions such as targeted education, product reformulation, repackaging, relabeling, or prohibition of sales of especially hazardous inhalant products to youth.
展示中毒控制数据作为国家药物滥用调查的辅助手段以及提供信息和重点预防工作的数据来源的价值。
全国中毒数据系统(NPDS)的数据由 60 个美国中毒中心实时收集和编制,当拨打者寻求中毒暴露的指导时。分析了 1993 年至 2008 年间报告的 35453 例吸入剂病例的人口统计学、地理位置、产品、结局和治疗场所数据。
向美国中毒控制中心报告的吸入剂病例的流行率从 1993 年到 2008 年下降了 33%。报告的病例中,年龄在 12 至 17 岁的儿童患病率最高,在 14 岁的儿童中达到高峰。与全国调查数据显示男女使用吸入剂的比例几乎相等形成对比,NPDS 吸入剂病例中 73.5%发生在男孩中,这表明男孩可能会采取更危险的使用行为。大多数病例(67.8%)在医疗机构中得到管理。报告了超过 3400 种不同的产品。推进剂、汽油和油漆是最常见的产品类别。推进剂是唯一随着时间推移而显著增加的产品类别。但丁烷、丙烷和空气清新剂的死亡率最高。所有吸入剂的流行率在西部山区各州和西弗吉尼亚州最高,但地理分布因产品类型而异。汽油对年幼的儿童来说是一个更大的问题;推进剂是年龄较大的儿童的问题。
NPDS 应该用于监测吸入剂滥用,因为它提供了关于使用者所经历的医疗结局的独特、及时和临床有用的信息,包括详细的产品信息(品牌和配方),并且可以用于识别实时的人口统计学、地理位置和产品趋势。将吸入剂预防工作集中在最危险的产品和受影响最严重的使用者上,可能会改善和促进战略预防,使干预措施如目标教育、产品配方改革、重新包装、重新标记或禁止向青年销售特别危险的吸入剂产品成为可能。