Aldemir Ebru, Akyel Betül, Altıntoprak A Ender, Aydın Rezzan, Coşkunol Hakan
Institute on Drug Abuse, Toxicology and Pharmaceutical Sciences, Ege University, 35040 İzmir, Turkey.
Department of Psychiatry, Ege University, 35040 İzmir, Turkey.
Case Rep Psychiatry. 2015;2015:643253. doi: 10.1155/2015/643253. Epub 2015 Jan 13.
Inhalant abuse is a problem that is getting more common all around the world. The increase in prevalence of inhalant abuse escalates morbidity and mortality rates. About 22% of people using inhalant have died at their first attempt. Particularly propane, butane, or propane-butane mixture has highest mortality rates. Sudden sniffing death syndrome, cardiomyopathy, central nervous system toxicity, hematological abnormalities, kidney toxicity, and hepatocellular toxicities are the major complications of inhalant abuse. Herein we present a patient with inhalant use disorder. At the age of 19, after a stressful life event he had unsuccessfully tried to suicide by inhaling LPG (liquefied petroleum gas, a mixture of butane and propane gases). After he realized that he had hallucinations and felt better during the inhalation, he started to abuse it. He was addicted to LPG for 10 years at the time of admission. Besides being dangerous for the society security, this intense level of LPG inhalation (12 liters a day) not giving any physical harm makes this case interesting.
吸入剂滥用是一个在全球范围内日益普遍的问题。吸入剂滥用患病率的上升导致发病率和死亡率攀升。约22%的吸入剂使用者在首次尝试时死亡。特别是丙烷、丁烷或丙烷 - 丁烷混合物的死亡率最高。突然 sniffing 死亡综合征、心肌病、中枢神经系统毒性、血液学异常、肾脏毒性和肝细胞毒性是吸入剂滥用的主要并发症。在此,我们介绍一名患有吸入剂使用障碍的患者。19岁时,在经历一次压力巨大的生活事件后,他通过吸入液化石油气(LPG,一种丁烷和丙烷气体的混合物)试图自杀但未成功。在他意识到吸入时会产生幻觉且感觉更好后,便开始滥用。入院时他已对LPG上瘾10年。除了对社会安全构成危险外,这种高强度的LPG吸入(每天12升)却未造成任何身体伤害,使得该病例颇具趣味性。 (注:原文中“sniffing”可能有误,推测可能是“sniff”,但按要求未作修改。)