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门静脉栓塞术后第一年肝脏体积变化的动力学

Kinetics of liver volume changes in the first year after portal vein embolization.

作者信息

Corrêa Danton, Schwartz Lawrence, Jarnagin William R, Tuorto Scott, DeMatteo Ronald, D'Angelica Michael, Allen Peter, Brown Karen, Fong Yuman

机构信息

Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

出版信息

Arch Surg. 2010 Apr;145(4):351-4; discussion 354-5. doi: 10.1001/archsurg.2010.42.

DOI:10.1001/archsurg.2010.42
PMID:20404285
Abstract

OBJECTIVE

To determine the time course of liver hypertrophy after portal vein embolization (PVE).

DESIGN

In a cohort study, computed tomography volumetrics were calculated for livers during a 1-year period after PVE.

SETTING

Tertiary liver cancer treatment center.

PATIENTS

Ten patients who were subjected to PVE and were found subsequently to not be candidates for liver resection.

INTERVENTION

Right PVE.

MAIN OUTCOME MEASURES

Left and right liver volumes.

RESULTS

The left liver continued growing for the entire first year after PVE, while the right liver continued to atrophy. The total volume remained remarkably constant.

CONCLUSION

Early PVE during administration of a course of neoadjuvant therapy would be beneficial for enhanced growth of the liver before liver resection.

摘要

目的

确定门静脉栓塞术(PVE)后肝脏肥大的时间进程。

设计

在一项队列研究中,对PVE后1年内的肝脏进行计算机断层扫描容积测量。

地点

三级肝癌治疗中心。

患者

10例接受PVE治疗且随后被发现不适合肝切除的患者。

干预措施

右门静脉栓塞术。

主要观察指标

左右肝体积。

结果

PVE后的整个第一年,左肝持续生长,而右肝持续萎缩。总体积保持显著恒定。

结论

在新辅助治疗疗程中早期进行PVE,将有利于肝切除术前肝脏的增强生长。

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