一名自身免疫性慢性活动性肝炎患者的血浆铜蓝蛋白值检测不到。
Undetectable caeruloplasmin values in a patient with autoimmune chronic active hepatitis.
作者信息
Ilan Y, Hillman M, Oren R, Galun E, Shalit M
机构信息
Department of Medicine A, Hadassah University Hospital, Jerusalem, Israel.
出版信息
Gut. 1991 May;32(5):549-50. doi: 10.1136/gut.32.5.549.
Caeruloplasmin is an alpha 2 protein produced in the liver that is responsible for transporting copper in the blood. Caeruloplasmin values are usually high in patients with chronic liver diseases, including chronic active hepatitis: low values, however, are characteristic of Wilson's disease. The case of a 17 year old woman with very low caeruloplasmin values and chronic active hepatitis of the lupoid type is described. Steroid treatment resulted in an increase in the caeruloplasmin concentration and clinical improvement.
铜蓝蛋白是一种在肝脏中产生的α2蛋白，负责在血液中运输铜。在包括慢性活动性肝炎在内的慢性肝病患者中，铜蓝蛋白值通常较高；然而，低值是威尔逊病的特征。本文描述了一名17岁女性患者，其铜蓝蛋白值极低，患有类狼疮型慢性活动性肝炎。类固醇治疗导致铜蓝蛋白浓度升高及临床症状改善。
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