Ramírez-Zamora Adolfo, Alarcón Tomás
Neurology Department, Stritch School of Medicine, Loyola University Chicago, Maywood, IL 60153, USA.
Neurol Res. 2010 Apr;32(3):229-37. doi: 10.1179/016164110X12644252260592.
Neurocysticercosis is a parasitic infection of the central nervous system caused by the larval stage of the tapeworm Taenia solium and is the most common parasitic infection involving the human nervous system. Neurocysticercosis represents one of the most common causes of symptomatic epilepsy in developing countries and is an increasing concern in industrialized nations.
We conducted a review of the medical literature regarding the current management of neurocysticercosis in Latin American countries.
Mexico and Brazil report the highest incidence of neurocysticercosis in Latin America. However, major obstacles interfere with an accurate determination of the prevalence of neurocysticercosis, including the lack of standardized and comprehensive epidemiological systems, intrinsic limitations of current immunological studies, the high cost of neuroimaging studies in rural communities and the presence of asymptomatic patients with neuroimaging characteristic compatible with neurocysticercosis. As such, the real prevalence of the disease and its burden are likely underestimated in Latin America. There is no universal consensus or guidelines for the management of different forms of the disease, but most experts agree in the use of antihelminithic therapy when viable cysts are encountered and with the use of corticosteroids in patients presenting with encephalitis.
Neurocysticercosis is a pleomorphic disease, with a broad spectrum of clinical and radiographic features. The medical management of neurocysticercosis is complex and needs to be individualized.
神经囊尾蚴病是由猪带绦虫幼虫阶段引起的中枢神经系统寄生虫感染,是累及人类神经系统最常见的寄生虫感染。神经囊尾蚴病是发展中国家症状性癫痫最常见的病因之一,在工业化国家也日益受到关注。
我们对拉丁美洲国家神经囊尾蚴病当前治疗方法的医学文献进行了综述。
墨西哥和巴西报告的拉丁美洲神经囊尾蚴病发病率最高。然而,主要障碍妨碍了对神经囊尾蚴病患病率的准确测定,包括缺乏标准化和全面的流行病学系统、当前免疫学研究的内在局限性、农村社区神经影像学检查成本高昂以及存在神经影像学特征与神经囊尾蚴病相符的无症状患者。因此,拉丁美洲该疾病的实际患病率及其负担可能被低估。对于该疾病不同形式的治疗,尚无普遍共识或指南,但大多数专家同意,遇到活囊时使用抗蠕虫疗法,对出现脑炎的患者使用皮质类固醇。
神经囊尾蚴病是一种多形性疾病,具有广泛的临床和影像学特征。神经囊尾蚴病的药物治疗很复杂,需要个体化。