希腊北部中风发病率的季节性变化：对8204例患者的10年研究。
Seasonal variation in the occurrence of stroke in Northern Greece: a 10 year study in 8204 patients.
作者信息
Karagiannis Asterios, Tziomalos Konstantinos, Mikhailidis Dimitri P, Semertzidis Panagiotis, Kountana Evangelia, Kakafika Anna I, Pagourelias Efstathios D, Athyros Vasilios G
机构信息
Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece.
出版信息
Neurol Res. 2010 Apr;32(3):326-31. doi: 10.1179/174313208X331608.
OBJECTIVE
The effect of seasonal variation on the occurrence of stroke remains controversial. The objective of this study was to determine whether there is a seasonal variation in the occurrence of stroke in Northern Greece.
METHODS
We recorded the seasonal stroke rates over a 10 year period (from January 1997 to December 2006) in 8204 patients in Northern Greece. The findings were analysed separately for ischemic stroke (IS), intracerebral hemorrhage (ICH), subarachnoid hemorrhage (SAH) and transient ischemic attack (TIA).
RESULTS
In patients with IS, there was a significant seasonal variation (p<0.001), with the peak incidence in spring (8.4% above average) and the lowest rate in summer (10.4% below average). There was no significant seasonal variation in the occurrence of the other stroke subtypes (ICH, SAH and TIA) when they were considered individually.
DISCUSSION
The seasonal effect on stroke incidence needs to be defined so as to improve the provision of preventive measures.
目的
季节变化对中风发生率的影响仍存在争议。本研究的目的是确定希腊北部中风的发生是否存在季节性变化。
方法
我们记录了希腊北部8204例患者在10年期间（从1997年1月至2006年12月）的季节性中风发病率。分别对缺血性中风（IS）、脑出血（ICH）、蛛网膜下腔出血（SAH）和短暂性脑缺血发作（TIA）的研究结果进行分析。
结果
在IS患者中，存在显著的季节性变化（p<0.001），春季发病率最高（高于平均水平8.4%），夏季发病率最低（低于平均水平10.4%）。单独考虑其他中风亚型（ICH、SAH和TIA）的发生情况时，未发现显著的季节性变化。
讨论
需要明确季节对中风发病率的影响，以改进预防措施的提供。
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