Department of Histopathology, The Royal National Orthopaedic Hospital, Stanmore, HA7 4LP, Middlesex, UK.
Int J Gynecol Pathol. 2010 May;29(3):256-9. doi: 10.1097/PGP.0b013e3181c03fc9.
A 13-year-old girl presented with pelvic pain and imaging revealed a large right ovarian cystic mass. Histologic examination showed a malignant myxoid tumor with chicken-wire vasculature characteristic of a myxoid liposarcoma. The morphologic appearances were supported by the presence of the rearrangement of the CHOP gene demonstrated by interphase fluorescent in situ hybridization. There was no evidence that this tumor represented metastatic disease. To the best of our knowledge, primary ovarian myxoid liposarcoma has not been previously reported in the English literature. We present the case and briefly discuss the differential diagnosis.
一位 13 岁女孩因盆腔疼痛就诊,影像学检查显示右侧卵巢有一个大的囊性肿块。组织学检查显示为恶性黏液样肿瘤,具有特征性的“鸡笼状”血管,符合黏液样脂肪肉瘤。间期荧光原位杂交显示 CHOP 基因重排,支持该形态学表现。该肿瘤无转移疾病的证据。据我们所知,英文文献中以前没有报道过原发性卵巢黏液样脂肪肉瘤。我们报告了这例病例,并简要讨论了鉴别诊断。