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特发性淋巴细胞性胸膜炎:2 例成人的影像学和高分辨率 CT 表现及治疗反应的变化。

Idiopathic lymphocytic pleuritis: radiographic and high-resolution CT appearances and changes in response to therapy in two adults.

机构信息

Department of Radiology, St. Vincent's University Hospital, Elm Park, Dublin 4, Ireland.

出版信息

Clin Imaging. 2010 May-Jun;34(3):226-30. doi: 10.1016/j.clinimag.2009.07.007.

DOI:10.1016/j.clinimag.2009.07.007
PMID:20416488
Abstract

Inflammatory conditions of the pleura characterized by a predominantly lymphocytic infiltrate are described in several disorders. The commonest underlying aetiologies include tuberculous infection, autoimmune disorders (particularly Sjogren's syndrome), and post coronary artery bypass graft surgery. Idiopathic lymphocytic pleuritis (ILP) is a rare form of diffuse pleural inflammation characterized by extensive lymphocytic infiltration for which no cause is found. Radiological descriptions of ILP are limited. We describe the radiographic and high-resolution computed tomography (HRCT) imaging features and response to corticosteroid therapy of ILP in two adults. Both patients presented with bilateral diffuse pleural thickening of >10 mm thickness extending >10 cm craniocaudally with small focal areas of atelectasis. Both cases demonstrated marked improvement in the degree and extent of pleural thickening and rounded atelectasis following corticosteroid therapy. HRCT provided a useful noninvasive method of assessing disease response to therapy.

摘要

胸膜的炎症性疾病以主要为淋巴细胞浸润为特征,在几种疾病中均有描述。最常见的潜在病因包括结核感染、自身免疫性疾病(特别是干燥综合征)和冠状动脉旁路移植术后。特发性淋巴细胞性胸膜炎(ILP)是一种罕见的弥漫性胸膜炎症形式,其特征为广泛的淋巴细胞浸润,但未发现病因。ILP 的放射学描述有限。我们描述了 2 例成人特发性淋巴细胞性胸膜炎的放射学和高分辨率计算机断层扫描(HRCT)成像特征以及对皮质类固醇治疗的反应。两名患者均表现为双侧弥漫性胸膜增厚>10 毫米,颅尾延伸>10 厘米,伴有小范围的肺不张。皮质类固醇治疗后,这两种情况的胸膜增厚程度和范围以及圆形肺不张均有明显改善。HRCT 提供了一种有用的非侵入性方法来评估疾病对治疗的反应。

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Intern Med. 2024 Jan 1;63(1):113-117. doi: 10.2169/internalmedicine.1240-22. Epub 2023 May 17.
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