Claussen Claus-F, Pandey Arti
Neurootologisches Forschungsinstitut der 4-G-Forschung E.V., Bad Kissingen, Germany.
Int Tinnitus J. 2009;15(2):174-84.
Vertigo and tinnitus are very frequent complaints. Often, we find multisensory syndromes combined with tinnitus, hearing impairment, vertigo, and nausea. From more than 10,000 cases, we evaluated 757 randomly selected neurootological patients suffering from endogenous tinnitus. First, we classified the 10,000 patients into those suffering from the basic tetrad of tinnitus forms: bruits, endogenous (maskable) tinnitus, exogenous (nonmaskable) tinnitus, and other syndromes such as the slow brainstem syndrome. Then, of all the endogenous tinnitus patients, we randomly selected our study sample (n = 757), and those patients underwent a complex neurosensory investigation, including neurootological history; classic audiometry; acoustic brainstem-evoked potentials; acoustic cortically evoked potentials; visually evoked potentials; electronystagmography of spontaneous, caloric, rotatory, and optokinetic nystagmus; and craniocorpography with several vestibulospinal tests. For this study, we primarily examined the historical findings. The statistical results demonstrate that tinnitus is interconnected to a multifactorial disease background with a broad spectrum of individual complaints. Finally, the topodiagnostics of the functional neurootometric analysis shows that this type of endogenous tinnitus constitutes decidedly more central than peripheral statoacoustic pathology.
眩晕和耳鸣是非常常见的症状。我们经常发现多感官综合征与耳鸣、听力障碍、眩晕和恶心同时出现。在10000多例病例中，我们对757例随机选取的患有内源性耳鸣的神经耳科患者进行了评估。首先，我们将这10000例患者分为患有耳鸣基本四联症的患者：杂音、内源性（可掩蔽性）耳鸣、外源性（不可掩蔽性）耳鸣以及其他综合征，如慢脑干综合征。然后，在所有内源性耳鸣患者中，我们随机选取了研究样本（n = 757），这些患者接受了一项复杂的神经感觉检查，包括神经耳科病史；经典听力测定；听性脑干诱发电位；听皮层诱发电位；视觉诱发电位；自发性、冷热、旋转和视动性眼震的眼震电图；以及进行了多项前庭脊髓试验的颅脑造影。在本研究中，我们主要检查了病史结果。统计结果表明，耳鸣与具有广泛个体症状的多因素疾病背景相互关联。最后，功能性神经耳科分析的定位诊断表明，这种类型的内源性耳鸣肯定比外周听觉病理更具中枢性。
