一种金丝雀痘-狂犬病重组病毒的功效研究。
Efficacy studies on a canarypox-rabies recombinant virus.
作者信息
Taylor J, Trimarchi C, Weinberg R, Languet B, Guillemin F, Desmettre P, Paoletti E
机构信息
Virogenetics Corporation, Troy, New York 12180.
出版信息
Vaccine. 1991 Mar;9(3):190-3. doi: 10.1016/0264-410x(91)90152-v.
PMID:2042391
Abstract
Recombinant avipox viruses have been developed expressing the rabies glycoprotein gene. A fowlpox-rabies recombinant has previously been shown to be protective against live rabies virus challenge in a number of non-avian species. This report describes the development of a canarypox-rabies recombinant. A comparison is made of the protective efficacy of this recombinant with other pox-rabies recombinants.
摘要
已经开发出表达狂犬病糖蛋白基因的重组禽痘病毒。先前已证明一种鸡痘-狂犬病重组体对许多非禽类物种的狂犬病病毒活攻毒具有保护作用。本报告描述了一种金丝雀痘-狂犬病重组体的开发情况。并将该重组体与其他痘苗-狂犬病重组体的保护效力进行了比较。
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