Pinto B, Rocha E
Invest Urol. 1977 Sep;15(2):155-7.
The excretion of uricine or yellowish-red pigment from uric acid stones and its binding by uric acid seems to affect the precipitation of uric acid. Uricine was determined by ion exchange chromatography followed by measurement of the alkaline fluorescence emission. The uricine urinary excretion and the uricine-uric acid potential binding were determined in 11 control subjects, 20 recurrent uric acid stone formers, seven calcium stone formers with hyperuricuria, and five gouty patients without urinary stone formation. Uricine excretion was increased in 11 uric acid stone formers, whereas it was normal in the rest of the patients. Uricine-uric acid potential binding was increased in many uric acid stone formers, despite the absence of uric acid urinary hyperexcretion, whereas it was normal in most of the calcium stone formers and was moderately increased in the gouty patients.
尿酸结石中尿酸或黄红色色素的排泄及其与尿酸的结合似乎会影响尿酸的沉淀。通过离子交换色谱法，随后测量碱性荧光发射来测定尿酸。在11名对照受试者、20名复发性尿酸结石形成者、7名伴有高尿酸血症的钙结石形成者和5名无尿路结石形成的痛风患者中，测定了尿酸排泄量和尿酸 - 尿酸潜在结合力。11名尿酸结石形成者的尿酸排泄量增加，而其余患者的尿酸排泄量正常。尽管没有尿酸尿排泄过多的情况，但许多尿酸结石形成者的尿酸 - 尿酸潜在结合力增加，而大多数钙结石形成者的尿酸 - 尿酸潜在结合力正常，痛风患者的尿酸 - 尿酸潜在结合力中度增加。
