Matsuhashi H, Onodera S, Hasebe N, Maruyama J, Honda H, Yamashita H, Tobise K
First Department of Internal Medicine, Asahikawa Medical College, Japan.
Angiology. 1991 Jun;42(6):504-11. doi: 10.1177/000331979104200611.
Transient pulsus alternans was induced by isosorbide dinitrate (ISDN) in a patient with postmyocarditis congestive heart failure under diuretic therapy. The severity and duration of pulsus alternans depended on the dose of ISDN. According to the echocardiographic and hemodynamic examinations, the superimposed preload reduction caused by ISDN combined with decreased blood volume owing to diuretic therapy most likely contributed to the development of pulsus alternans.
在一名接受利尿剂治疗的心肌炎后充血性心力衰竭患者中，硝酸异山梨酯（ISDN）诱发了短暂性交替脉。交替脉的严重程度和持续时间取决于ISDN的剂量。根据超声心动图和血流动力学检查，ISDN导致的叠加性前负荷降低与利尿剂治疗引起的血容量减少相结合，很可能促成了交替脉的发生。
