Wang L
School of Biomedical Sciences, Charles Sturt University, Wagga Wagga, New South Wales, Australia.
Exp Clin Cardiol. 2001 Fall;6(3):167-71.
Despite the explosion of new information on nitric oxide (NO), important questions about its role in regulating cardiac electrophysiology remain unanswered. Recent in vitro and in vivo animal studies have discovered a number of new electrophysiological properties of NO, some of which may contribute to a reduction in fatal arrhythmias induced by acute myocardial ischemia. This review summarizes the influences of NO on heart rate, atrioventricular conduction, ventricular repolarization and the development of ventricular arrhythmias during acute myocardial ischemia.
尽管关于一氧化氮(NO)的新信息大量涌现,但关于其在调节心脏电生理方面的作用的重要问题仍未得到解答。最近的体外和体内动物研究发现了NO的一些新的电生理特性,其中一些特性可能有助于减少急性心肌缺血诱发的致命性心律失常。本综述总结了急性心肌缺血期间NO对心率、房室传导、心室复极和室性心律失常发生发展的影响。