[Hormonal therapy in systemic lupus erythematosus].

Estrogens favor the development and/or exacerbation of systemic lupus erythematosus (SLE). Numerous reports have described the association between estrogens exposure (oral contraceptives and menopause hormonal therapy) and development or exacerbation of SLE. Some new studies showed benefit from oral contraceptives and other hormonal therapies without a change in lupus activity but with increased risk of thrombosis. Hormonal therapy in SLE patients should be individual according to clinical presentation and progression of the disease.