Steinmetz H, Volkmann J, Jäncke L, Freund H J
Department of Neurology, Heinrich-Heine University, Düsseldorf, Germany.
Ann Neurol. 1991 Mar;29(3):315-9. doi: 10.1002/ana.410290314.
Asymmetry of the planum temporale, a language-related intrasylvian area on the superior temporal gyrus, is the most remarkable anatomical left-right asymmetry of the human brain. The in vivo application of magnetic resonance morphometry in 52 healthy volunteers (26 dextrals and 26 sinistrals) revealed that planum temporale asymmetry is correlated with hand dominance. Left-handers had a significantly lesser degree of leftward planum temporale asymmetry than right-handers. Thus, a structural-functional relation exists in cerebral asymmetry. The correlation is likely to reflect language representation. Because familial sinistrality influenced the anatomical pattern in left-handers and planum temporale asymmetry is already present in the newborn, prenatal factors must play an important role in the development of functional laterality.
颞平面的不对称性是人类大脑最显著的左右解剖学不对称现象，颞平面是颞上回上一个与语言相关的侧裂内区域。对52名健康志愿者（26名右利手和26名左利手）进行的磁共振形态测量活体应用显示，颞平面不对称性与利手相关。左利手的颞平面左向不对称程度明显低于右利手。因此，大脑不对称中存在结构-功能关系。这种相关性可能反映了语言表征。由于家族性左利手影响左利手的解剖模式，且颞平面不对称在新生儿中就已存在，产前因素必定在功能偏侧性的发展中起重要作用。
