Hunter New England Population Health, Wallsend, NSW, Australia.
Epidemiol Infect. 2011 Mar;139(3):437-45. doi: 10.1017/S0950268810000944. Epub 2010 Apr 30.
Listeriosis is a foodborne disease associated with significant mortality. This study attempts to identify risk factors for sporadic listeriosis in Australia. Information on underlying illnesses was obtained from cases' treating doctors and other risk factors were elicited from the patient or a surrogate. We attempted to recruit two controls per case matched on age and primary underlying immune condition. Between November 2001 and December 2004 we recruited 136 cases and 97 controls. Of perinatal cases, living in a household where a language other than English was spoken was the main risk factor associated with listeriosis (OR 11·3, 95% CI 1·5-undefined). Of non-perinatal cases we identified the following risk factors for listeriosis: prior hospitalization (OR 4·3, 95% CI 1·0-18·3), use of gastric acid inhibitors (OR 9·4, 95% CI 2·4-37·4), and consumption of camembert (OR 4·7, 95% CI 1·1-20·6). Forty percent of cases with prior hospitalization were exposed to high-risk foods during hospitalization.
李斯特菌病是一种食源性疾病，与高死亡率相关。本研究旨在确定澳大利亚散发性李斯特菌病的危险因素。基础疾病信息由病例的主治医生提供，其他危险因素则由患者或其代理人提供。我们试图按照年龄和主要潜在免疫状况匹配每个病例的两名对照。在 2001 年 11 月至 2004 年 12 月期间，我们共招募了 136 例病例和 97 名对照。对于围产期病例，居住在讲英语以外语言的家庭是李斯特菌病的主要危险因素（OR 11.3，95%CI 1.5-未定义）。对于非围产期病例，我们确定了李斯特菌病的以下危险因素：既往住院治疗（OR 4.3，95%CI 1.0-18.3）、使用胃酸抑制剂（OR 9.4，95%CI 2.4-37.4）和食用卡门培尔干酪（OR 4.7，95%CI 1.1-20.6）。40%有既往住院史的病例在住院期间接触了高危食品。
