Pérez José A Hermida, Palmes M de la Paz Pérez, Ferrer Juan Francisco Loro, Urdangarain Otto Ochoa, Nuñez Abdel Buduen
Superior Institute of Medical Sciences, University of Camaguey, Cuba.
Arch Esp Urol. 2010 Apr;63(3):173-87.
To investigate epidemiologic, etiopathogenic and clinical factors associated with emergency renal colic (RC). METHODS ANDS RESULTS: We performed a prospective cross-sectional multicenter case-control study of 146 patients treated for RC at emergency departments. Data collected included age, sex, localization/severity of pain, symptoms, personal/family medical history, urine analysis, etiopathogenic factors, chemical composition of the lithiasis, and x-ray studies. Comparative statistical analysis was performed using SPSS 12.2 software. RC was more frequent in men; maximum incidence was between 31-50 years for both sex, with 36.3% in men and 21.23% in women; 60.27% of patients rated pain as severe; 140 RC patients (95.89%) had urologic antecedents vs. 15 (10.27%) controls without RC (p<0.001). The most frequent presentation (93.83%) was sudden intense lumbar-abdominal or lumbar pain; 23.28% of RC patients had family history for urinary lithiasis vs. 6.16% controls (p<0,001). Most RC patients were seen during summer (36.58%), 82% of RC patients drank <2L of water daily vs. 18.49% in non-RC patients (p<0.001). Hematuria was found in 132 (90.41%) patients with RC vs. 17 (11.64%) in those without (p<0.001). Lithiasis was observed by KUB x-ray in 42.10% of RC patients vs. 57.89% controls, most frequent calculi composition was calcium oxalate monohydrate and dehydrate (61,2%).
The incidence of urinary lithiasis and RC in our health care area shows a male predominance. The characteristic pain of RC is severe and appears suddenly. It starts in the back (lumbar region), below the ribs, radiating towards the groin and external genitals (testicles in man or major lips in woman) on the same side. Nausea and vomiting are frequent. Family history of urinary lithiasis and low water intake are risk factors that need to be investigated. Occupations associated with a sedentary life style or with a hot, dry workplace show a higher incidence of lithiasis. A hot, dry climate favours the formation of urinary lithiasis and the highest incidence of lithiasis is in the summer, during the months of July and August. The most frequent component of urolithiasis in our study, as well as in other studies, was calcium oxalate monohydrate and dihydrate.
探讨与急诊肾绞痛(RC)相关的流行病学、病因及临床因素。
我们对急诊科治疗的146例RC患者进行了一项前瞻性横断面多中心病例对照研究。收集的数据包括年龄、性别、疼痛部位/严重程度、症状、个人/家族病史、尿液分析、病因、结石化学成分及X线检查。使用SPSS 12.2软件进行比较统计分析。RC在男性中更为常见;两性的最高发病率均在31 - 50岁之间,男性为36.3%,女性为21.23%;60.27%的患者将疼痛评为重度;140例RC患者(95.89%)有泌尿系统病史,而15例无RC的对照组患者中只有15例(10.27%)有泌尿系统病史(p<0.001)。最常见的表现(93.83%)是突然发作的剧烈腰腹部或腰痛;23.28%的RC患者有尿石症家族史,而对照组为6.16%(p<0.001)。大多数RC患者在夏季就诊(36.58%),82%的RC患者每日饮水量<2L,而非RC患者中这一比例为18.49%(p<0.001)。132例(90.41%)RC患者出现血尿,而无RC的患者中只有17例(11.64%)出现血尿(p<0.001)。通过腹部平片(KUB)X线检查发现42.10%的RC患者有结石,而对照组为57.89%,最常见的结石成分是一水合草酸钙和二水合草酸钙(61.2%)。
我们医疗保健区域内尿石症和RC的发病率显示男性占主导。RC的典型疼痛剧烈且突然发作。疼痛始于背部(腰部区域)、肋骨下方,向同侧腹股沟和外生殖器(男性为睾丸,女性为大阴唇)放射。恶心和呕吐很常见。尿石症家族史和低饮水量是需要调查的危险因素。与久坐生活方式或炎热干燥工作场所相关的职业尿石症发病率较高。炎热干燥的气候有利于尿石症的形成,尿石症发病率最高的是夏季的7月和8月。在我们的研究以及其他研究中,尿石症最常见的成分是一水合草酸钙和二水合草酸钙。