Johns Hopkins University, Baltimore, MD 21287-3325, USA.
J Am Acad Child Adolesc Psychiatry. 2010 May;49(5):514-23; quiz 530. doi: 10.1097/00004583-201005000-00012.
This retrospective cohort study examined the risk for suicide, psychiatric hospitalization, and violent criminal convictions among offspring of parents who died from suicide, accidents, and other causes.
Population-based data from multiple Swedish national registers were linked from 1969 to 2004. Participants were 44,397 offspring of suicide decedents, 41,467 offspring of accident decedents, 417,365 offspring of parents who died by other causes, and 3,807,867 offspring of alive parents. We estimated risk by mode of parental death (suicide, accident, other) and offspring age at parental death (childhood, adolescence, young adulthood).
Offspring of suicide decedents were at greater risk for suicide than offspring of alive parents (incidence rate ratio [IRR] = 1.9; 95% confidence interval [CI] = 1.4 to 2.5), whereas offspring of accident decedents and other parental death were not at increased risk (p < .001). The risk for offspring suicide differed by the developmental period during which parental suicide occurred. Child and adolescent offspring of suicide decedents were at threefold greater risk for suicide (IRR = 3.0; 95% CI = 1.7 to 5.3; IRR = 3.1, 95% CI = 2.1 to 4.6, respectively). Young adults were not at increased risk for suicide (IRR = 1.3; 95% CI = 0.9 to 1.9). Offspring of suicide decedents had an especially high risk of hospitalization for suicide attempt, depressive, psychotic, and personality disorders. Child survivors of parental suicide were at particularly high risk for hospitalization for drug disorders and psychosis. All offspring who experienced parental death, regardless of mode or age, were at increased risk for violent criminal convictions.
Mode of parental death and offspring age at parental death are associated with offspring long-term risk for suicide and hospitalization for specific psychiatric disorders.
本回顾性队列研究调查了父母因自杀、意外和其他原因死亡的子女发生自杀、精神病住院和暴力犯罪的风险。
从 1969 年至 2004 年,从多个瑞典国家登记处获取基于人群的数据,并进行链接。参与者包括 44397 名自杀死者的子女、41467 名意外死者的子女、417365 名其他死因死者的子女以及 3807867 名在世父母的子女。我们通过父母死亡的方式(自杀、意外、其他)和子女父母死亡时的年龄(儿童期、青春期、青年期)来评估风险。
与在世父母的子女相比,自杀死者的子女自杀风险更高(发病率比[IRR] = 1.9;95%置信区间[CI] = 1.4 至 2.5),而意外死者和其他死因死者的子女自杀风险没有增加(p <.001)。子女自杀的风险因父母自杀发生的发育阶段而异。自杀死者的儿童和青少年子女自杀风险增加三倍(IRR = 3.0;95% CI = 1.7 至 5.3;IRR = 3.1,95% CI = 2.1 至 4.6)。青年期子女自杀风险没有增加(IRR = 1.3;95% CI = 0.9 至 1.9)。自杀死者的子女尤其有自杀未遂、抑郁、精神病和人格障碍住院的高风险。自杀父母的儿童幸存者尤其有药物障碍和精神病住院的高风险。经历过父母死亡的所有子女,无论死亡方式或年龄如何,暴力犯罪定罪的风险都增加。
父母死亡的方式和子女父母死亡时的年龄与子女长期自杀风险和特定精神障碍住院风险相关。